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103968 Plin1

103968

Plin1

perilipin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition perilipin 1

研究结论

Date Results Publications
2020-08-15 19:03:00 [CRISPR/Cas9 knockout plin1 enhances lipolysis in 3T3-L1 adipocytes]. 32748596
2020-08-01 13:00:00 Sulfhydration is a novel post-translation modification of perilipin 1. Perilipin 1 sulfhydration lowers its phosphorylation to inhibit lipolysis. Cystathionine gamma lyase is major key enzyme of hydrogen sulfide generation controlling perilipin 1 sulfhydration. 31706571
2019-06-01 11:52:00 Overexpressed PLIN1 in macrophages had a protected role against atheroma progression in ApoeKO in the absence of changes in gonadal fat mass or plasma lipid levels, presumably due to modification of the stability and/or inflammatory profile of macrophages. 29407594
2019-05-04 11:48:00 Hypertension in Plin1-/- mice might occur as a deleterious consequence of perivascular adipose tissue dysfunction. 26521150
2019-03-02 10:06:00 Plin1 is required to restrain fat loss and pro-inflammatory responses in adipose tissue by reducing futile lipolysis to maintain metabolic homeostasis. 30042231

名称对应

Type IDs
Synonymous 6030432J05Rik, Peri, Plin
Gene
UniProtKB-ID: PLIN1_MOUSE
UniprotKB: Q8CGN5
UniParc: UPI0001B78F66, UPI0001B78F68, UPI0001B78F67, UPI00001931C2
EMBL: CH466543, AY161165, AK031445, BC096685
Ensembl: ENSMUSG00000030546
KO: mmu:103968
Nucleutide sequences
EMBL-CDS: AAH96685.1, EDL07055.1, BAC27409.1, AAN77870.1
Ensembl_TRS: ENSMUST00000205915, ENSMUST00000032762, ENSMUST00000178257
Protein sequencees
Ensembl_PRO: ENSMUSP00000136996, ENSMUSP00000146028, ENSMUSP00000032762
RefSeq: NP_783571.2, NP_001106942.1, XP_011249078.1
Others
UniRef100: UniRef100_Q8CGN5
UniRef90: UniRef90_Q8CGN5
UniRef50: UniRef50_Q8CGN5
UniGene: Mm.254917
CCDS: CCDS21385.1

全选

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