| Type | Description |
|---|---|
| Definition | myosin light chain 12B |
| Date | Results | Publications |
|---|---|---|
| 2012-05-26 11:07:00 | phosphorylated MRLC temporally controls its own accumulation, but not that of actin, in cultured mammalian cells. | 22374324 |
| 2012-05-05 10:50:00 | The study data show that manipulation of the activation sites (Thr18/Ser19) significantly alters myosin II function in a number of these assays while manipulation of the putative inhibitory sites (Ser1/Ser2/Thr9) does not. | 22136066 |
| 2012-03-17 11:44:00 | These results suggest that 2P-MRLC has a role different from that of 1P-MRLC at the midzone, and is not a subunit of myosin II. | 22166199 |
| 2010-01-21 00:00:00 | These results suggest that EGCG inhibits the cell growth by reducing the MRLC phosphorylation and this effect is mediated by the 67LR. | 15946647 |
| 2009-01-28 15:10:00 | Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | 19165527 |
| Type | IDs |
|---|---|
| Synonymous | MLC-B, MRLC2 |
| Gene |
UniProtKB-ID:
ML12B_HUMAN
UniprotKB:
O14950
UniParc:
UPI0000024704
EMBL:
D82058,
D50372,
BC004994,
AB046614,
AK291726,
CH471113,
U26162,
AY320408
Ensembl:
ENSG00000118680
KO:
hsa:103910
|
| Nucleutide sequences |
EMBL-CDS:
EAX01677.1,
BAA23323.1,
EAX01676.1,
BAB62403.1,
AAH04994.1,
EAX01675.1,
AAA67367.1,
BAF84415.1,
AAP73808.1,
BAB88918.1
Ensembl_TRS:
ENST00000581193,
ENST00000584539,
ENST00000237500,
ENST00000648965,
ENST00000400175
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383037,
ENSP00000237500,
ENSP00000496809,
ENSP00000463559,
ENSP00000464464
RefSeq:
NP_001138417.1,
NP_001138416.1,
NP_291024.1
|
| Others |
UniRef100:
UniRef100_O14950
UniRef90:
UniRef90_O14950
UniRef50:
UniRef50_O14950
UniGene:
Hs.190086,
Hs.464472
CCDS:
CCDS11831.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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