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10383 TUBB4B

10383

TUBB4B

tubulin beta 4B class IVb

protein-coding

Homo sapiens

基因描述

Type Description
Definition tubulin beta 4B class IVb

研究结论

Date Results Publications
2020-05-16 11:54:00 The authors uncovered that decomposition of microtubules associated with the decrease of TUBB4B protein observed during epithelial-mesenchymal transition of colon cancer cells is critical for the regulation of cell polarization and control of vimentin localization and function. 31375012
2018-06-20 17:59:00 nuclear beta(II)-tubulin can modulate Notch signaling through interaction with notch1 receptor intracellular domain in cancer cells 15548702
2018-05-19 10:12:00 TUBB3 and TUBB4 are necessary for the transport and proper localization of N-cadherin within the plasma membrane. 28648944
2018-01-06 10:52:00 The authors identified TUBB4B mutations as the cause of a previously unreported autosomal-dominant syndrome manifesting as early-onset and severe photoreceptor and cochlear cell loss. 29198720
2012-06-30 11:50:00 The results od this study found that betaI-tubulin protein expression was decreased in the anterior cingulate cortex and increased in the dorsolateral prefrontal cortex, but not changed in superior temporal gyrus or hippocampus in schizophrenia. 22264600

名称对应

Type IDs
Synonymous Beta2, LCAEOD, TUBB2, TUBB2C
Gene
UniProtKB-ID: TBB4B_HUMAN
UniprotKB: P68371
UniParc: UPI000000D966
EMBL: BC002885, BC012835, BC019359, BC071889, BX255925, BC001911, BC004188, BC007889, X02344, BC019829, BC039175, BC002783
Ensembl: ENSG00000188229
KO: hsa:10383
Nucleutide sequences
EMBL-CDS: AAH02783.1, AAH04188.1, AAH12835.1, AAH71889.1, AAH39175.1, AAH19829.1, AAH07889.1, AAH19359.1, CAA26203.1, AAH01911.1, AAH02885.1
Ensembl_TRS: ENST00000340384
Protein sequencees
Ensembl_PRO: ENSP00000341289
RefSeq: NP_006079.1
Others
UniRef100: UniRef100_P68371
UniRef90: UniRef90_P68371
UniRef50: UniRef50_P68371
UniGene: Hs.433615
CCDS: CCDS7039.1

全选

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研究热度

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