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103733 Tubg1

103733

Tubg1

tubulin, gamma 1

protein-coding

Mus musculus

基因描述

Type Description
Definition tubulin, gamma 1

研究结论

Date Results Publications
2019-06-15 12:28:00 Study investigated the consequences of four human malformations of cortical development-related TUBG1 variants by using in utero electroporation and a knock-in Tubg1Y92C/+ mouse model and show that pathogenic TUBG1 variants affect neuronal positioning by disrupting neuronal migration and affecting microtubule dynamics rather than centrosomal positioning or nucleation ability. 31086189
2014-05-03 12:24:00 Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis. 24098540
2013-09-21 12:27:00 Data suggest that localization of Tubg1 (and Plk1 [polo-like kinase 1]) to spindle poles during oocyte meiotic maturation/oogenesis (metaphase I/II) requires participation of Uchl5ip/Haus7 (HAUS augmin-like complex subunit 7). 23182369
2011-01-15 11:16:00 a direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome 20224777
2010-01-21 00:00:00 SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin. 19648910

名称对应

Type IDs
Synonymous 1500010O08Rik, AI451582, AI503389, GCP-1, Tubg
Gene
UniProtKB-ID: TBG1_MOUSE, Q6F4J1_MOUSE
UniprotKB: P83887, Q6F4J1
UniParc: UPI0000025A1F
EMBL: AK154019, AB158480, BC006581
Ensembl: ENSMUSG00000035198
KO: mmu:103733
Nucleutide sequences
EMBL-CDS: AAH06581.1, BAE32319.1, BAD27264.1
Ensembl_TRS: ENSMUST00000043680
Protein sequencees
Ensembl_PRO: ENSMUSP00000048036
RefSeq: NP_598785.1, XP_017169700.1
Others
UniRef100: UniRef100_P83887
UniRef90: UniRef90_P83887
UniRef50: UniRef50_P83887
UniGene: Mm.479145
CCDS: CCDS25451.1

全选

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研究热度

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