| Type | Description |
|---|---|
| Definition | cysteine dioxygenase type 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | Prediction of Efficacy of Postoperative Chemotherapy by of CDO1 in Gastric Cancer. | 32777557 |
| 2020-02-29 12:15:00 | CDO1 is preferentially silenced by promoter methylation in human non-small cell lung cancers (NSCLC) harboring mutations in KEAP1, the negative regulator of NRF2. CDO1 silencing promotes proliferation of NSCLC by limiting the futile metabolism of cysteine to the wasteful and toxic byproducts cysteine sulfinic acid and sulfite (SO3(2-)), and depletion of cellular NADPH. | 31107239 |
| 2020-02-22 12:52:00 | Data show that nitric oxide ((*)NO), an oxygen surrogate, similarly binds to uncross-linked F2-Tyr157 cysteine dioxygenase (CDO) as in wild-type CDO. | 30946568 |
| 2020-01-04 11:31:00 | Anchorage independent growth was reduced in several gastric cancer cell lines due to forced expression of the CDO1 gene, suggesting that abnormal CDO1 gene expression may represent distant metastatic ability. | 30934021 |
| 2019-10-26 10:34:00 | The CDO1 gene shows extremely cancer-specific hypermethylation, and it can be a prognostic marker in small bowel cancer. | 30677088 |
| Type | IDs |
|---|---|
| Synonymous | CDO-I |
| Gene |
UniProtKB-ID:
CDO1_HUMAN
UniprotKB:
Q16878
UniParc:
UPI000016A7B9
EMBL:
Z23010,
Z31357,
U60232,
BC024241,
CR536540,
D85782,
D85777,
U78979,
U80055,
CH471086,
AK314231
Ensembl:
ENSG00000129596
KO:
hsa:1036
|
| Nucleutide sequences |
EMBL-CDS:
EAW48957.1,
CAA80552.1,
BAA12872.1,
BAG36901.1,
BAA12873.1,
CAA83234.1,
CAG38777.1,
AAH24241.1,
AAB58352.1
Ensembl_TRS:
ENST00000250535
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000250535
RefSeq:
NP_001310494.1,
NP_001792.2,
NP_001310496.1,
NP_001310495.1
|
| Others |
UniRef100:
UniRef100_Q16878
UniRef90:
UniRef90_Q16878
UniRef50:
UniRef50_Q16878
UniGene:
Hs.442378
CCDS:
CCDS4121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员