| Type | Description |
|---|---|
| Definition | F-box and WD-40 domain protein 11 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:46:00 | Investigated beta-TrCP function in Sertoli cells by generating mice with targeted deletion of the beta-TrCP2 gene in Sertoli cells on a background of whole-body beta-TrCP1 knockout. Loss of beta-TrCP in Sertoli cells caused infertility due to a reduction in the number of mature sperm. | 30391586 |
| 2019-01-09 15:30:00 | beta-TrCP was identified as a novel interacting partner of ASK1 that is capable of ubiquitinating and degrading ASK1 through the ubiquitin-proteasome system. These findings suggest that beta-TrCP is capable of suppressing oxidative stress-induced caspase 3-dependent apoptosis through suppression of ASK1. | 30031111 |
| 2015-12-19 11:19:00 | The mTOR pathway promotes cell proliferation via beta-TrCP2-dependent p19(Arf) degradation under nutrient-rich conditions. | 26240281 |
| 2011-04-01 17:24:00 | Data show that beta-TrCP2 and beta-TrCP1 target PER2 protein in vitro, and also show that the beta-TrCP binding site of PER2 is recognized by both beta-TrCP1 and beta-TrCP2 [beta-TrCP2]. | 18782782 |
| Type | IDs |
|---|---|
| Synonymous | 2310065A07Rik, AA536858, BTRC2, BTRCP2, Fbxw1b, HOS |
| Gene |
UniProtKB-ID:
FBW1B_MOUSE
UniprotKB:
Q5SRY7
UniParc:
UPI00005AD396,
UPI00000EA592,
UPI000047055C,
UPI0000027FA9
EMBL:
AK166226,
AK041532,
AK160086,
AK149139,
AL669844,
BC034261,
AL669951,
AY038079,
AK168667,
AK152181
Ensembl:
ENSMUSG00000020271
KO:
mmu:103583
|
| Nucleutide sequences |
EMBL-CDS:
BAE28749.1,
BAC30975.1,
BAE40519.1,
BAE38644.1,
BAE35617.1,
BAE31012.1,
AAH34261.1,
AAK72095.1
Ensembl_TRS:
ENSMUST00000109366,
ENSMUST00000093205,
ENSMUST00000076383
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000090893,
ENSMUSP00000075721,
ENSMUSP00000104991
RefSeq:
NP_001258277.1,
NP_001350282.1,
XP_006514496.1,
NP_001258278.1,
NP_001350284.1,
NP_001258276.1,
NP_001350283.1,
NP_598776.1
|
| Others |
UniRef100:
UniRef100_Q5SRY7
UniRef90:
UniRef90_Q9UKB1
UniRef50:
UniRef50_Q9Y297
UniGene:
Mm.28017,
Mm.491286
CCDS:
CCDS70157.1,
CCDS70158.1,
CCDS36125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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