| Type | Description |
|---|---|
| Definition | aldo-keto reductase family 1 member A1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | (5-Hydroxy-4-oxo-2-styryl-4H-pyridin-1-yl)-acetic Acid Derivatives as Multifunctional Aldose Reductase Inhibitors. | 33158254 |
| 2018-07-21 10:34:00 | Data (including data from studies in knockout and transgenic mice) suggest that AKR1A1 in liver is involved in bioactivation of xenobiotic/carcinogen thioacetamide (TAA); Akr1a-/- knockout mice are resistant to TAA-induced liver injury/hepatotoxicity. | 29763686 |
| 2014-07-12 12:21:00 | prostaglandin F synthase activity of human and bovine aldo-keto reductases | 23747692 |
| 2013-06-22 12:10:00 | AKR1A1 could be involved in the metabolism of 4-hydroxynonenal and play a role in the resistance to oxidative stress | 23643085 |
| 2011-08-27 10:36:00 | AKR1A1 has little effect on the production of gamma-hydroxybutyrate | 21276435 |
| Type | IDs |
|---|---|
| Synonymous | ALDR1, ALR, ARM, DD3, HEL-S-6 |
| Gene |
UniProtKB-ID:
AK1A1_HUMAN,
V9HWI0_HUMAN
UniprotKB:
P14550,
V9HWI0
UniParc:
UPI000013D31D
EMBL:
CR457010,
BT007003,
EU794588,
BC000670,
CH471059,
AF036680,
AF036683,
J04794,
AF036682,
AF112484,
AF112485,
EU668319,
AF036681,
BC005394,
AK293083,
AL355480
Ensembl:
ENSG00000117448
KO:
hsa:10327
|
| Nucleutide sequences |
EMBL-CDS:
CAG33291.1,
AAP35649.1,
AAH05394.1,
EAX06971.1,
AAB92369.1,
AAA51711.1,
AAF01260.1,
BAF85772.1,
EAX06974.1,
EAX06970.1,
EAX06972.1,
AAH00670.1,
ACJ13642.1,
ACF94472.1
Ensembl_TRS:
ENST00000621846,
ENST00000351829,
ENST00000372070
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000312606,
ENSP00000480713,
ENSP00000361140
RefSeq:
NP_006057.1,
XP_011538793.1,
NP_001189342.1,
NP_697021.1,
XP_011538794.1,
NP_001189343.1
|
| Others |
UniRef100:
UniRef100_P14550
UniRef90:
UniRef90_P14550
UniRef50:
UniRef50_P14550
UniGene:
Hs.474584,
Hs.721160
CCDS:
CCDS523.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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