| Type | Description |
|---|---|
| Definition | Ras related GTP binding B |
| Date | Results | Publications |
|---|---|---|
| 2017-11-25 15:11:00 | Data suggest DNM2/RRAGB- (or DNM2/RRAGC-)dependent endocytosis of extracellular amino acids (AAs) plays critical role in mTORC1 transport/activation; recruitment of mTORC1 from cytoplasm to lysosome is suppressed by DNM2 inhibition; AA deprivation appears to be main cause of mTORC1 inactivation via DNM2 inhibition. (RHEB = Ras homolog enriched in brain; DNM2 = dynamin II; RRAG = Ras-related GTP binding protein) | 28808055 |
| 2012-10-27 10:12:00 | Inhibition of glutaminolysis prevents GTP loading of RagB and lysosomal translocation and subsequent activation of mTORC1. | 22749528 |
| Type | IDs |
|---|---|
| Synonymous | RAGB, bA465E19.1 |
| Gene |
UniProtKB-ID:
RRAGB_HUMAN
UniprotKB:
Q5VZM2
UniParc:
UPI00001AE856,
UPI0000073CF4
EMBL:
AL139277,
BC034726,
AL831926,
CH471154,
X90530,
AL159987,
AK289407
Ensembl:
ENSG00000083750
KO:
hsa:10325
|
| Nucleutide sequences |
EMBL-CDS:
EAW93229.1,
CAA62132.1,
BAF82096.1,
AAH34726.1,
CAD38586.1
Ensembl_TRS:
ENST00000374941,
ENST00000262850
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364077,
ENSP00000262850
RefSeq:
NP_001340942.1,
NP_057740.2,
NP_006055.3,
XP_016884707.1,
NP_001340940.1
|
| Others |
UniRef100:
UniRef100_Q5VZM2
UniRef90:
UniRef90_Q5VZM2
UniRef50:
UniRef50_Q5VZM2
UniGene:
Hs.50282
CCDS:
CCDS14372.1,
CCDS14371.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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