| Type | Description |
|---|---|
| Definition | LanC like 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 12:28:00 | Results suggest that LanCL1 protects cells from oxidative stress, and promotes cell proliferation. LanCL1 reduces cell death via suppression of JNK signaling pathway. | 29416001 |
| 2019-08-03 11:03:00 | Oxygen and glucose deprivation (OGD) exposure induced a temporal increase and persistent decreases in the expression of LanCL1 at both mRNA and protein levels. Overexpression of LanCL1 by lentivirus transfection preserved cell viability, reduced lactate dehydrogenase release and attenuated apoptosis after OGD. LanCL1 stimulated mitochondrial enzyme activities and SOD2 deacetylation in a Sirt3-dependent manner. | 30075199 |
| 2013-01-05 11:21:00 | Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense. | 22891245 |
| 2010-01-21 00:00:00 | the crystal structures of human LanCL1, both free of and complexed with glutathione, revealing glutathione binding to a zinc ion at the putative active site formed by conserved GxxG motifs | 19528316 |
| Type | IDs |
|---|---|
| Synonymous | GPR69A, p40 |
| Gene |
UniProtKB-ID:
LANC1_HUMAN,
B2R602_HUMAN,
A0A024R3Z5_HUMAN,
Q53TN2_HUMAN
UniprotKB:
O43813,
B2R602,
A0A024R3Z5,
Q53TN2
UniParc:
UPI0000073D7C,
UPI0000EE36B5,
UPI0001750516
EMBL:
CH471063,
AJ289239,
AC007970,
AJ289236,
AJ289238,
BC028685,
AK312381,
AJ289237,
Y11395
Ensembl:
ENSG00000115365
KO:
hsa:10314
|
| Nucleutide sequences |
EMBL-CDS:
AAH28685.1,
CAA72205.1,
CAC21950.1,
BAG35299.1,
EAW70491.1,
EAW70488.1,
EAW70487.1,
EAW70490.1,
AAY14696.1,
EAW70489.1
Gene_ORFName:
hCG_16716,
hCG_16716
Ensembl_TRS:
ENST00000233714,
ENST00000431941,
ENST00000443314,
ENST00000441020,
ENST00000450366
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000393323,
ENSP00000388713,
ENSP00000397646,
ENSP00000233714,
ENSP00000393597
RefSeq:
NP_001130047.1,
NP_001130046.1,
XP_005246300.1,
NP_006046.1
|
| Others |
UniRef100:
UniRef100_O43813,
UniRef100_B2R602
UniRef90:
UniRef90_F1MVX2,
UniRef90_O43813
UniRef50:
UniRef50_O43813
UniGene:
Hs.13351
CCDS:
CCDS2392.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员