| Type | Description |
|---|---|
| Definition | solute carrier family 6 (neurotransmitter transporter), member 15 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 10:38:00 | Our study demonstrates a role for reduced Slc6a15, a neutral amino acid transporter, in nucleus accumbens (NAc) in depression and stress susceptibility. The reduction of Slc6a15 occurs selectively in the NAc D2-neurons. Genetic reduction of Slc6a15 induces susceptibility to a subthreshold stress, while genetic overexpression in D2-neurons prevents social avoidance after chronic social defeat stress. | 28576941 |
| 2016-09-24 12:03:00 | Slc6a15 plays a role in modulating emotional behavior, possibly mediated by its impact on glutamatergic neurotransmission. | 26585320 |
| 2016-06-28 11:49:00 | SLC6A15 regulates the activity of the brain glutamatergic system through the proline-glutamate biosynthesis pathway, affecting hippocampal neurochemistry and consequently behavior. | 26228428 |
| 2010-01-21 00:00:00 | Slc6a15 knockout mice demonstrate only modest alterations in rotarod performance with aging and lack reproducible alterations in other motor, memory, anxiety or olfactory tests | 17931606 |
| 2010-01-21 00:00:00 | The structure and function of B0AT2 are reported. | 16185194 |
| Type | IDs |
|---|---|
| Synonymous | AA536730, AI326450, AI326451, v7-3 |
| Gene |
UniProtKB-ID:
S6A15_MOUSE
UniprotKB:
Q8BG16
UniParc:
UPI000002177F
EMBL:
AY149280,
AY149282,
AM085111,
CH466539,
AK036136,
BC076593,
AY149281
Ensembl:
ENSMUSG00000019894
KO:
mmu:103098
|
| Nucleutide sequences |
EMBL-CDS:
AAH76593.1,
AAN75437.1,
EDL21677.1,
BAC29315.1,
CAJ29896.1,
EDL21676.1,
AAN75438.1,
AAN75439.1
Ensembl_TRS:
ENSMUST00000179636,
ENSMUST00000074204
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000073829,
ENSMUSP00000136676
RefSeq:
NP_001239259.1,
NP_780537.1,
XP_036011342.1,
NP_001345750.1,
XP_006513047.1,
XP_006513046.1
|
| Others |
UniRef100:
UniRef100_Q8BG16
UniRef90:
UniRef90_Q8BG16
UniRef50:
UniRef50_Q9H2J7
UniGene:
Mm.458408
CCDS:
CCDS24156.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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