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10309 CCNO

10309

CCNO

cyclin O

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin O

研究结论

Date Results Publications
2017-05-13 17:14:00 This study presents the crystal structure of the DDB1-DCAF1-HIV-1-Vpr-uracil-DNA glycosylase (cyclin U) complex. 27571178
2016-12-17 10:51:00 CCNO is mutated more frequently than expected from the rare previous clinical case reports, leads to severe clinical manifestations, and should therefore be considered an important differential diagnosis of mucociliary clearance disorders. 26777464
2014-08-09 11:01:00 CCNO mutations have a role in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia 24747639
2010-11-02 17:37:00 This publication corrected the mistaken attribution of uracil DNA glycosylase activity to this gene. 8419333
2010-11-02 17:33:00 This publication initially attributed 'uracil-DNA glycosylase' activity to this gene and named it UNG2, but a later publication (PubMed ID: 8419333) more correctly identified UNG2/CCNO as a member of the cyclin protein family. 2001396

名称对应

Type IDs
Synonymous CCNU, CILD29, UDG2
Gene
UniProtKB-ID: CCNO_HUMAN
UniprotKB: P22674
UniParc: UPI000020C764, UPI0000071CCB
EMBL: CH471123, AK290030, AC026704, X52486, M87499, AK026075, BC004877
Ensembl: ENSG00000152669
KO: hsa:10309
Nucleutide sequences
EMBL-CDS: AAB05817.1, BAF82719.1, BAB15351.1, CAA36728.1, EAW54913.1, AAH04877.1
Ensembl_TRS: ENST00000501463, ENST00000282572
Protein sequencees
Ensembl_PRO: ENSP00000282572, ENSP00000422485
RefSeq: NP_066970.3
Others
UniRef100: UniRef100_P22674
UniRef90: UniRef90_P22674
UniRef50: UniRef50_P22674
UniGene: Hs.3041
CCDS: CCDS34157.1

全选

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