| Type | Description |
|---|---|
| Definition | functional intergenic repeating RNA element |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:30:00 | Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome. | 33247132 |
| 2020-05-30 12:59:00 | examined the in vivo contribution of these loci by generating mice carrying a single or double deletion of Firre and Dxz4. We found that these mutants are viable, fertile and show no defect in random or imprinted X-chromosome inactivation | 31738164 |
| 2020-02-29 11:08:00 | the Firre locus produces a trans-acting long noncoding RNA that has physiological roles in hematopoiesis. | 31723143 |
| 2018-12-22 10:07:00 | neither the deletion of the CTCF locus nor the ectopic insertion of Firre cDNA or its ectopic expression are sufficient to alter topologically associated domains in a sex-specific or allele-specific manner | 29654311 |
| 2015-12-05 11:10:00 | Firre is X-linked and expressed from a macrosatellite repeat locus associated with a cluster of CTCF and cohesin binding sites, and is preferentially located adjacent to the nucleolus | 25887447 |
| Type | IDs |
|---|---|
| Synonymous | 5830467J12Rik, 6720401G13Rik, AW048145 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Mm.482523
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33247132 |
Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome. Nat Commun He Fang , Giancarlo Bonora , Jordan P Lewandowski , Jitendra Thakur , Galina N Filippova , Steven Henikoff , Jay Shendure , Zhijun Duan , John L Rinn , Xinxian Deng , William S Noble , Christine M Disteche |
2020-11-27 | - |
| 31738164 |
In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation. Elife Daniel Andergassen , Zachary D Smith , Jordan P Lewandowski , Chiara Gerhardinger , Alexander Meissner , John L Rinn |
2019-11-18 | - |
| 31723143 |
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis. Nat Commun Jordan P Lewandowski , James C Lee , Taeyoung Hwang , Hongjae Sunwoo , Jill M Goldstein , Abigail F Groff , Nydia P Chang , William Mallard , Adam Williams , Jorge Henao-Meija , Richard A Flavell , Jeannie T Lee , Chiara Gerhardinger , Amy J Wagers , John L Rinn |
2019-11-13 | - |
| 29654311 |
A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus. Nat Commun A Rasim Barutcu , Philipp G Maass , Jordan P Lewandowski , Catherine L Weiner , John L Rinn |
2018-04-13 | - |
| 26048247 |
Regulation of the ESC transcriptome by nuclear long noncoding RNAs. Genome Res. Jan H Bergmann , Jingjing Li , Mélanie A Eckersley-Maslin , Frank Rigo , Susan M Freier , David L Spector |
2015-09-01 | - |
| 26283634 |
Regulatory networks of non-coding RNAs in brown/beige adipogenesis. Biosci. Rep. Shaohai Xu , Peng Chen , Lei Sun |
2015-01-01 |
Firre,
Lncbate1,
FIRRE
|
| 25887447 |
Genome Biol. Fan Yang , Xinxian Deng , Wenxiu Ma , Joel B Berletch , Natalia Rabaia , Gengze Wei , James M Moore , Galina N Filippova , Jun Xu , Yajuan Liu , William S Noble , Jay Shendure , Christine M Disteche |
2015-01-01 |
Firre,
Ctcf,
FIRRE
|
| 24463464 |
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nat. Struct. Mol. Biol. Ezgi Hacisuleyman , Loyal A Goff , Cole Trapnell , Adam Williams , Jorge Henao-Mejia , Lei Sun , Patrick McClanahan , David G Hendrickson , Martin Sauvageau , David R Kelley , Michael Morse , Jesse Engreitz , Eric S Lander , Mitch Guttman , Harvey F Lodish , Richard Flavell , Arjun Raj , John L Rinn |
2014-02-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
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