| Type | Description |
|---|---|
| Definition | membrane associated ring-CH-type finger 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | The E3 ubiquitin ligase MARCHF6 as a metabolic integrator in cholesterol synthesis and beyond. | 33049405 |
| 2020-07-04 10:30:00 | the E3 ubiquitin ligase membrane-associated ring-CH-type finger 6 (MARCH6), known to control earlier rate-limiting steps in cholesterol synthesis, also control levels of LDM and the terminal cholesterol synthesis enzyme, 24-dehydrocholesterol reductase. | 31904814 |
| 2020-04-18 12:36:00 | UBE2J2 as an important partner of MARCH6 for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis. | 30658189 |
| 2020-03-07 10:50:00 | MARCH6 and AR expression are strongly correlated in primary prostate cancer tissues. This correlation is unrelated to androgen receptor signalling. MARCH6 and AR share common regulation by the transcription factor Sp1. | 31422115 |
| 2020-02-29 11:06:00 | TTTTA/TTTCA repeat expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3. | 31664039 |
| Type | IDs |
|---|---|
| Synonymous | DOA10, MARCH-VI, RNF176, TEB4 |
| Gene |
UniProtKB-ID:
MARH6_HUMAN
UniprotKB:
O60337
UniParc:
UPI00017A7AFF,
UPI00001B94D6,
UPI00017A73FE
EMBL:
BC136461,
AB011169,
BC136462,
AK300034,
BC046148,
AC012640,
AF009301,
AK296585,
CH471102,
AC092336,
BC142694,
BC142679
Ensembl:
ENSG00000145495
KO:
hsa:10299
|
| Nucleutide sequences |
EMBL-CDS:
BAG61845.1,
BAA25523.1,
EAX08066.1,
AAB66840.1,
AAI36463.1,
AAI42695.1,
AAI42680.1,
EAX08065.1,
BAG59204.1,
AAH46148.1,
AAI36462.1
Ensembl_TRS:
ENST00000449913,
ENST00000503788,
ENST00000274140
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000274140,
ENSP00000414643,
ENSP00000425930
RefSeq:
NP_005876.2,
NP_001257589.1,
NP_001257590.1,
XP_011512236.1,
XP_011512238.1,
XP_011512234.1,
XP_016864433.1
|
| Others |
UniRef100:
UniRef100_O60337
UniRef90:
UniRef90_O60337
UniRef50:
UniRef50_O60337
UniGene:
Hs.432862
CCDS:
CCDS34135.1,
CCDS59488.1,
CCDS59487.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员