| Type | Description |
|---|---|
| Definition | leukocyte immunoglobulin like receptor B2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:26:00 | The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma. | 32620162 |
| 2021-01-09 13:26:00 | The Interaction of LILRB2 with HLA-B Is Associated with Psoriasis Susceptibility. | 31874134 |
| 2019-08-31 10:17:00 | Study revealed the coexpression of ILT4 and human leukocyte antigenG (HLAG) in tissues of human primary colorectal cancer (CRC) and its association with older age, advanced stage, regional lymph node involvement and poor overall survival time. Results indicated that the interaction of ILT4 and its ligand HLAG promotes CRC progression through AKT and ERK signal activation. | 30942436 |
| 2019-05-25 10:04:00 | Mechanistically, LILRB2 enhances the SHP2/CaMK1/CREB signaling pathways to support the expansion and migration of the endometrial cancer cells. | 30343889 |
| 2019-02-23 13:15:00 | LILRB2 is overexpressed in human HCC tissues and is associated with patients' poor survival. LILRB2 may serve as a marker for poor prognosis of HCC. | 30589055 |
| Type | IDs |
|---|---|
| Synonymous | CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10 |
| Gene |
UniProtKB-ID:
A2IXV5_HUMAN
UniprotKB:
A2IXV5
UniParc:
UPI0000114074
EMBL:
AF004231
KO:
hsa:10288
|
| Nucleutide sequences |
EMBL-CDS:
AAB67711.1
|
| Protein sequencees |
RefSeq:
NP_001265334.2,
NP_001265332.2,
NP_001074447.2,
NP_001265335.2,
NP_005865.3,
NP_001265333.2
|
| Others |
UniRef100:
UniRef100_A2IXV5
UniRef90:
UniRef90_Q8N423
UniRef50:
UniRef50_Q8NHL6
UniGene:
Hs.655652
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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