| Type | Description |
|---|---|
| Definition | plastin 3 (T-isoform) |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 10:28:00 | PLS3 coadministration improves the phenotype beyond the antisense oligonucleotides, demonstrating the potential utility of combinatorial therapeutics in spinal muscular atrophy that target SMN-independent and SMN-dependent pathways. | 28289706 |
| 2019-05-11 10:15:00 | Regulation of osteoclastogenesis and bone remodeling via the PLS3-NKRF-NFkappaB-NFATC1 axis unveils a novel possibility to counteract osteoporosis. | 30204862 |
| 2019-02-23 11:21:00 | Of the six biomarkers, only COMP and DPP4 showed high and SPP1 moderate correlation with the spinal muscular atrophy phenotype. PLS3 overexpression neither influenced the SMN level nor the six biomarkers, supporting the hypothesis that PLS3 acts as an independent protective modifier. | 30188931 |
| 2018-08-11 12:15:00 | Data indicate there are 6 mutations in Plastin-3 (PLS3) responsible for X-linked osteoporosis, and the mutation c.759_760insAAT (p.Ala253_Leu254insAsn) is located in exon 8. | 28646489 |
| 2018-03-17 11:16:00 | Depletion of Pls3 transcripts in mouse embryos caused basement membrane and polarity defects in the epidermis which were secondary to the disruption of the basement membrane but had little effect on cell adhesion and differentiation. | 28559444 |
| Type | IDs |
|---|---|
| Synonymous | AI115446, AL024105 |
| Gene |
UniProtKB-ID:
PLST_MOUSE,
Q3UKB1_MOUSE,
Q3UJG9_MOUSE,
B1AX58_MOUSE
UniprotKB:
Q99K51,
Q3UKB1,
Q3UJG9,
B1AX58
UniParc:
UPI0000D681A5,
UPI00005AC4CF,
UPI00005AC56C,
UPI00000236ED
EMBL:
AK146087,
AK160501,
AK146455,
CH466576,
BC005459,
AL805920,
AB182243
Ensembl:
ENSMUSG00000016382
KO:
mmu:102866
|
| Nucleutide sequences |
EMBL-CDS:
BAE35826.1,
EDL29216.1,
AAH05459.1,
BAD23918.1,
BAE26890.1,
BAE27186.1
Ensembl_TRS:
ENSMUST00000114059,
ENSMUST00000033547,
ENSMUST00000114057,
ENSMUST00000114058
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109693,
ENSMUSP00000109691,
ENSMUSP00000033547,
ENSMUSP00000109692
RefSeq:
NP_001159926.1,
XP_036017657.1,
NP_001159925.1,
NP_001333448.1,
XP_006527796.1,
NP_001333449.1,
XP_006527794.1,
NP_663604.1
|
| Others |
UniRef100:
UniRef100_B1AX58,
UniRef100_Q3UKB1,
UniRef100_Q99K51
UniRef90:
UniRef90_P13797,
UniRef90_H9G9I2
UniRef50:
UniRef50_H0ZPX2,
UniRef50_Q61233
UniGene:
Mm.28777
CCDS:
CCDS30243.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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