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102800311 TP53COR1

102800311

TP53COR1

tumor protein p53 pathway corepressor 1

ncRNA

Homo sapiens

基因描述

Type Description
Definition tumor protein p53 pathway corepressor 1

研究结论

Date Results Publications
2020-06-27 12:40:00 LincRNA-p21 participates in thoracic aortic aneurysms (TAA) by regulating the proliferation and apoptosis of vascular smooth muscle cells through the activation of TGF-b1 signaling pathway. 30302790
2020-06-27 10:40:00 Results demonstrated that linc-p21 expression level was downregulated in gastric cancer (GC) cells and tissues and its overexpression suppressed the GC cell growth, cell cycle, and migration as well as the radiosensitivity by regulating the beta-catenin signaling pathway. These data suggested that lincRNA-p21 acted as a tumor suppressor gene in the development of GC. 30484893
2020-04-18 10:19:00 lincRNA-p21 suppresses the bladder cancer cell growth through inhibiting glutaminase and glutamine catabolism. 30902882
2019-07-06 13:00:00 Study found that lncRNA-p21 is highly expressed in the neuroendocrine prostate cancer (NEPC) patients derived xenograft tissues. Results from cell lines and human clinical sample surveys also revealed that lncRNA-p21 expression is up-regulated in NEPC and antiandrogen enzalutamide treatment could increase the lncRNA-p21 to induce the neuroendocrine differentiation. 31189930
2019-06-08 12:43:00 LincRNA-p21 is aberrantly upregulated in non-small cell lung cancer and inhibits cell apoptosis by decreasing PUMA expression. 30556447

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Type IDs
Synonymous TRP53COR1, linc-p21, lincRNA-p21