| Type | Description |
|---|---|
| Definition | sigma non-opioid intracellular receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis. | 31696229 |
| 2021-04-03 13:38:00 | Urinary bladder sigma-1 receptors: A new target for cystitis treatment. | 32105755 |
| 2021-04-03 13:35:00 | Wildtype sigma1 receptor and the receptor agonist improve ALS-associated mutation-induced insolubility and toxicity. | 33453999 |
| 2021-03-13 13:25:00 | Homozygosity for rs17775810 Minor Allele Associated With Reduced Mortality of COVID-19 in the UK Biobank Cohort. | 33622890 |
| 2021-03-13 13:20:00 | The ALS-related sigma1R E102Q Mutant Eludes Ligand Control and Exhibits Anomalous Response to Calcium. | 33020464 |
| Type | IDs |
|---|---|
| Synonymous | ALS16, DSMA2, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R |
| Gene |
UniProtKB-ID:
SGMR1_HUMAN,
B4DR71_HUMAN,
A2A3U5_HUMAN
UniprotKB:
Q99720,
B4DR71,
A2A3U5
UniParc:
UPI00000340A6,
UPI00000724E7,
UPI0000073493,
UPI0000047D51,
UPI00017A7AAF,
UPI0000D9DEA0
EMBL:
DQ644568,
AL450283,
CR457075,
AY633611,
U79528,
U75283,
AK098451,
AK222899,
AK291092,
DQ656583,
CH471071,
AF001976,
BC007839,
BC004899,
AF226604,
AF001977,
AK299130,
DQ647702
Ensembl:
ENSG00000147955
KO:
hsa:10280
|
| Nucleutide sequences |
EMBL-CDS:
AAH04899.1,
AAB51238.1,
AAH07839.1,
ABG46369.1,
BAD96619.1,
EAW58434.1,
BAC05307.1,
AAF64280.1,
ABG29111.1,
AAC04507.1,
CAG33356.1,
EAW58431.1,
ABG36559.1,
AAV33304.1,
AAB50402.1,
BAG61183.1,
EAW58435.1,
EAW58436.1,
BAF83781.1
Gene_ORFName:
AAG8,
hCG_20471
Ensembl_TRS:
ENST00000477726,
ENST00000353468,
ENST00000277010
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000420022,
ENSP00000434453,
ENSP00000277010
RefSeq:
NP_001269138.1,
NP_005857.1,
NP_001269134.1,
NP_001269135.1,
NP_671513.1,
NP_001269137.1,
NP_001269136.1
|
| Others |
UniRef100:
UniRef100_B4DR71,
UniRef100_Q99720,
UniRef100_A2A3U5
UniRef90:
UniRef90_A0A5F5PNS1,
UniRef90_A0A2Y9LJP4,
UniRef90_Q99720
UniRef50:
UniRef50_Q99720,
UniRef50_A0A5F5PNS1
UniGene:
Hs.522087
CCDS:
CCDS6562.1,
CCDS6563.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员