| Type | Description |
|---|---|
| Definition | ubiquitination factor E4B |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:34:00 | neuroblastoma cells with low UBE4B levels were significantly more sensitive to combined EGFR and inhibition than parental cells. These findings may have potential therapeutic implications for patients with 1p36 chromosome LOH and low tumor UBE4B expression. | 31475882 |
| 2019-09-07 12:44:00 | Phosphatase PGAM5 (phosphoglycerate mutase 5) and deubiquitinase OTUB1 (ovarian tumor domain containing ubiquitin aldehyde binding protein 1) were confirmed as E4B substrates, and beta-catenin and CDK4 (cyclin-dependent kinase 4) were confirmed as CHIP substrates. | 29326975 |
| 2017-09-02 12:23:00 | miR-1301 functions as a tumor suppressor that inhibits tumor cell migration and invasion in multiple human cancer cells by regulating the UBE4B-p53 pathway. | 28483517 |
| 2016-11-12 11:48:00 | UBE4B promotes endogenous phospho-p53(S15) and phospho-p53(S392) degradation in response to gamma irradiation. UBE4B plays an important role in regulating phosphorylated p53 following DNA damage. | 26673821 |
| 2016-05-28 10:10:00 | UBE4B overexpression promotes the oncogenic properties of HCC and is correlated with an unfavorable prognosis in HCC patients. | 25557723 |
| Type | IDs |
|---|---|
| Synonymous | E4, HDNB1, UBOX3, UFD2, UFD2A |
| Gene |
UniProtKB-ID:
UBE4B_HUMAN
UniprotKB:
O95155
UniParc:
UPI0000071F1D,
UPI000006F352,
UPI000218D791,
UPI0000137944
EMBL:
AL096841,
AF043117,
AB014584,
AK292444,
AB028839,
JF289274,
AL590639,
BC093696,
AF091093,
AF331520
Ensembl:
ENSG00000130939
KO:
hsa:10277
|
| Nucleutide sequences |
EMBL-CDS:
BAA31659.3,
AEK06331.1,
AAD02233.1,
BAB40446.1,
AAH93696.1,
AAK69622.1,
AAC72962.1,
BAF85133.1
Ensembl_TRS:
ENST00000672724,
ENST00000253251,
ENST00000343090
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253251,
ENSP00000500453,
ENSP00000343001
RefSeq:
XP_011538792.1,
XP_016855525.1,
XP_016855524.1,
NP_001099032.1,
XP_011538790.1,
NP_006039.2,
XP_005263479.1,
XP_011538791.1
|
| Others |
UniRef100:
UniRef100_O95155
UniRef90:
UniRef90_O95155
UniRef50:
UniRef50_Q9ES00
UniGene:
Hs.593974
CCDS:
CCDS41245.1,
CCDS110.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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