| Type | Description |
|---|---|
| Definition | stromal antigen 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:31:00 | Whole Exome Sequencing Identifies Cohesin Component STAG1 Mutation in de novo Acute Myeloid Leukemia (FAB M2): A Pilot Study with Cytogenetics, Clinical and Prognostic Implications. | 33639073 |
| 2020-09-12 16:01:00 | Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. | 31495782 |
| 2020-08-01 11:20:00 | Study provides a comprehensive review of the function of STAG1/2 in human physiology and disease and an integrative analysis of available omics data on STAG alterations in a wide array of cancers, comprising 53 691 patients and 1067 cell lines. | 31421907 |
| 2019-09-21 10:49:00 | We uncovered the cohesion subunit SA1 as a putative synthetic-essential target in cancers carrying inactivating mutations of its paralog, SA2. In SA2-deficient Ewing sarcoma and bladder cancer, further depletion of SA1 profoundly and specifically suppressed cancer cell proliferation, survival, and tumorigenic potential. | 29649003 |
| 2018-12-01 11:53:00 | The SNP but not wild-type had profound alterations in SA-1 expression with miR-29b inhibitor. | 29471289 |
| Type | IDs |
|---|---|
| Synonymous | MRD47, SA1, SCC3A |
| Gene |
UniProtKB-ID:
STAG1_HUMAN,
Q4LE48_HUMAN
UniprotKB:
Q8WVM7,
Q4LE48
UniParc:
UPI0000231C67,
UPI000054C925,
UPI000020A2DE
EMBL:
Z75330,
AC128712,
BC064699,
AC117382,
AC069514,
AB210023,
AC107425,
BC017735,
AC069524
Ensembl:
ENSG00000118007
KO:
hsa:10274
|
| Nucleutide sequences |
EMBL-CDS:
AAH17735.1,
CAA99731.1,
AAH64699.1,
BAE06105.1
Ensembl_TRS:
ENST00000383202,
ENST00000236698
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000372689,
ENSP00000236698
RefSeq:
XP_016861013.1,
XP_011510631.1,
XP_016861012.1,
NP_005853.2,
XP_011510633.1,
XP_016861014.1
|
| Others |
UniRef100:
UniRef100_Q8WVM7
UniRef90:
UniRef90_Q8WVM7
UniRef50:
UniRef50_Q8N3U4
UniGene:
Hs.412586
CCDS:
CCDS3090.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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