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10268 RAMP3

10268

RAMP3

receptor activity modifying protein 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition receptor activity modifying protein 3

研究结论

Date Results Publications
2019-04-06 12:40:00 high RAMP3 expression is an independent prognostic factor of favorable overall survival and recurrence-free survival in patients with HCC and its expression might reduce the negative effect of TP53 mutation on survival. 29882679
2016-12-17 12:06:00 interaction of RAMP2 or RAMP3 with CLR induces conformational variation in the juxtamembrane region, yielding distinct binding pockets, probably via an allosteric mechanism. 27013657
2015-01-31 13:15:00 the AM system is widely expressed in human thymus from newborns; both AM1 receptor components CLR and RAMP2, but not RAMP3, are not associated with the plasma membrane of TECs and thymocytes but are located intracellularly, notably in the nucleus 24831942
2014-10-11 12:49:00 Data suggest isoforms of RAMP modulate accessibility of peptides to residues situated on CALCRL (calcitonin receptor-like receptor) N-terminal domain; RAMP3/RAMP2/RAMP1 appear to alter accessibility of specific residues at CALCRL-RAMP interface. 24199627
2014-07-19 11:45:00 The expression of RAMP3 is downregulated in the fetal lung with increasing gestational age. 24169318

名称对应

Type IDs
Gene
UniProtKB-ID: RAMP3_HUMAN, A4D2L1_HUMAN
UniprotKB: O60896, A4D2L1
UniParc: UPI0000134303
EMBL: CH236960, BC022304, AJ001016, BC053852, AY265459, AC004844, AK311871, CH471128
Ensembl: ENSG00000122679
KO: hsa:10268
Nucleutide sequences
EMBL-CDS: AAH53852.1, CAA04474.1, AAP23300.1, AAH22304.1, EAW61048.1, BAG34812.1, EAL23743.1
Gene_ORFName: hCG_17148, tcag7.792
Ensembl_TRS: ENST00000481345, ENST00000242249
Protein sequencees
Ensembl_PRO: ENSP00000242249, ENSP00000419012
RefSeq: XP_006715694.1, XP_016867155.1, NP_005847.1
Others
UniRef100: UniRef100_O60896
UniRef90: UniRef90_O60896
UniRef50: UniRef50_O60896
UniGene: Hs.25691
CCDS: CCDS5503.1

全选

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