| Type | Description |
|---|---|
| Definition | receptor activity modifying protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:32:00 | in nestin/hRAMP1 transgenic mice, hypertension caused by Ang II or phenylephrine was greatly attenuated, and associated autonomic dysregulation and increased sympathetic vasomotor tone were diminished or abolished. | 29297736 |
| 2020-01-25 10:18:00 | Based on the finding that an acylated chimeric ADM/ADM2 analog potently stimulates CLR/RAMP1 and 2 signaling, we hypothesized that the binding domain of this analog could have potent inhibitory activity on CLR/RAMP receptors. | 31150417 |
| 2019-03-23 11:33:00 | structure of the human CGRP receptor in complex with CGRP and the Gs-protein heterotrimer at 3.3 A global resolution, determined by Volta phase-plate cryo-electron microscopy | 30209400 |
| 2018-02-24 10:12:00 | T-A-T RAMP1 gene haplotype might have utility as a genetic marker for Essential Hypertension and that the RAMP1 gene may be associated with increased susceptibility to Essential Hypertension in a Japanese population. | 28181496 |
| 2017-08-12 10:25:00 | Data suggest CGRP receptor (CGRPR) ECL2 (extracellular loop 2 domain) enables interaction with N-terminal residues of CGRP; this provides evidence for dual involvement of ECL2 in two-domain binding model of CGRP/CGRPR interaction; CGRPR is obligate heterodimer of CLR/RAMP1. (CGRP = calcitonin gene-related peptide; CLR = calcitonin receptor-like receptor; RAMP1 = receptor [calcitonin] activity modifying protein 1) | 28691801 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RAMP1_HUMAN,
E9PC20_HUMAN
UniprotKB:
O60894,
E9PC20
UniParc:
UPI00001342FF,
UPI0000208DA2
EMBL:
CH471063,
AC012076,
CR542032,
AY265457,
AJ001014,
KF510799,
AC016776,
BC000548,
CR542044
Ensembl:
ENSG00000132329
KO:
hsa:10267
|
| Nucleutide sequences |
EMBL-CDS:
EAW71127.1,
CAA04472.1,
CAG46841.1,
CAG46829.1,
AAH00548.1,
AAP23298.1
Ensembl_TRS:
ENST00000254661,
ENST00000403885,
ENST00000404910,
ENST00000409726
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000254661,
ENSP00000384688,
ENSP00000386720,
ENSP00000386046
RefSeq:
NP_005846.1,
XP_016858644.1,
XP_016858641.1,
NP_001295282.1,
XP_016858645.1,
XP_016858643.1,
XP_016858642.1
|
| Others |
UniRef100:
UniRef100_O60894
UniRef90:
UniRef90_O60894
UniRef50:
UniRef50_O60894
UniGene:
Hs.471783
CCDS:
CCDS2522.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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