| Type | Description |
|---|---|
| Definition | CD276 antigen |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | B7-H3 augments the pro-angiogenic function of tumor-associated macrophages and acts as a novel adjuvant target for triple-negative breast cancer therapy. | 33153969 |
| 2018-10-20 10:31:00 | These results indicated an important role for B7-H3 in the development of Th1 and Th2 cells in a murine model of asthma and its proinflammatory effects are not dependent on TLR2 signaling. | 28094276 |
| 2018-04-28 11:18:00 | These results demonstrate that B7H3 substantially ameliorates LPS-induced Acute lung injury and this protection afforded by B7H3 is predominantly associated with its inhibitory effect on pulmonary migration and infiltration | 27515382 |
| 2018-04-21 11:21:00 | Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function | 28685773 |
| 2017-08-12 12:21:00 | blockage of NF-kappaB p65 and/or MAPK p38 with their specific inhibitors strongly attenuated B7-H3-amplified inflammatory response with significantly reduced proinflammatory cytokine and chemokine production, and markedly ameliorated B7-H3-exacerbated disruption of blood-brain barrier and severity of disease status in S. pneumoniae-infected mice. | 28141831 |
| Type | IDs |
|---|---|
| Synonymous | 6030411F23Rik, AU016588, B7RP-2, B7h3 |
| Gene |
UniProtKB-ID:
CD276_MOUSE,
A6MDC5_MOUSE
UniprotKB:
Q8VE98,
A6MDC5
UniParc:
UPI0000024BEB
EMBL:
DQ832276,
BC056608,
AK155114,
BC019436,
AY190318
Ensembl:
ENSMUSG00000035914
KO:
mmu:102657
|
| Nucleutide sequences |
EMBL-CDS:
AAH19436.1,
BAE33058.1,
AAH56608.1,
AAP04007.1,
ABI30210.1
Ensembl_TRS:
ENSMUST00000039788,
ENSMUST00000165365
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000042681,
ENSMUSP00000129418
RefSeq:
NP_598744.1
|
| Others |
UniRef100:
UniRef100_Q8VE98
UniRef90:
UniRef90_Q8VE98
UniRef50:
UniRef50_Q8VE98
UniGene:
Mm.5356
CCDS:
CCDS23244.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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