| Type | Description |
|---|---|
| Definition | iroquois homeobox 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 11:01:00 | our findings suggested that IRX5 promoted CRC metastasis by inhibiting the RHOA-ROCK1-LIMK1 axis, which correlates with a poor prognosis | 31432570 |
| 2019-12-21 10:17:00 | Promotion of IRX3 signalling or inhibition of IRX5 signalling could be a route towards differentiation therapy for Wilms tumour, in which WNT5A is a candidate molecule for enforced tubular maturation. | 30246301 |
| 2016-10-08 11:41:00 | Authors identify a novel association that implicates the IRX5 gene region in obesity and compare our results with previously derived interaction data for the region. | 26642925 |
| 2012-08-04 11:22:00 | Our findings suggest that IRX proteins integrate combinatorial transcriptional inputs to regulate key signaling molecules involved in the ontogeny of multiple organs during embryogenesis and homeostasis. | 22581230 |
| 2010-01-21 00:00:00 | involved in transcriptional regulation of heart morphogenesis | 16527195 |
| Type | IDs |
|---|---|
| Synonymous | HMMS, IRX-2a, IRXB2 |
| Gene |
UniProtKB-ID:
IRX5_HUMAN
UniprotKB:
P78411
UniParc:
UPI00001B6458,
UPI0000140A28,
UPI00001FF1CD
EMBL:
U90309,
AY335945,
AY335944,
U90304,
AC106738
Ensembl:
ENSG00000176842
KO:
hsa:10265
|
| Nucleutide sequences |
EMBL-CDS:
AAB50002.1,
AAQ16551.1,
AAQ16550.1,
AAB50007.1
Ensembl_TRS:
ENST00000394636,
ENST00000320990
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378132,
ENSP00000316250
RefSeq:
XP_011521111.1,
NP_005844.4,
NP_001239126.1
|
| Others |
UniRef100:
UniRef100_P78411
UniRef90:
UniRef90_P78411
UniRef50:
UniRef50_P78411
UniGene:
Hs.435730
CCDS:
CCDS58462.1,
CCDS10751.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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