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102626 Mapkapk3

102626

Mapkapk3

mitogen-activated protein kinase-activated protein kinase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition mitogen-activated protein kinase-activated protein kinase 3

研究结论

Date Results Publications
2020-05-30 10:25:00 IL-33-activated murine mast cells control the dichotomy between RORgammat(+) and Helios(+) Tregs via the MK2/3-mediated IL-6 production in vitro 31334837
2020-05-23 12:43:00 The MK2/3 are the only LPS-induced kinases for S52 and S178 of TTP and the role of MK2 and MK3 in the regulation of TNF biosynthesis is not restricted to phosphorylation of TTP at S52/S178 but includes independent processes, which could involve other TTP phosphorylations. 31527197
2017-08-19 12:01:00 this study shows that the loss of MK3 in mast cells decreases the IL-33-induced leukocyte recruitment and the resulting skin inflammation 27694493
2016-12-17 10:04:00 A dominant mutation in causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium. 26744326
2016-03-12 10:34:00 MK2/3 cascade plays a strategic role in controlling synaptic plasticity and cognition. 25134715

名称对应

Type IDs
Synonymous 3PK, AI874665, MAPKAP-K3, MAPKAP3, MK-3, MK3, MapkKapk3
Gene
UniProtKB-ID: MAPK3_MOUSE, Q09HN3_MOUSE
UniprotKB: Q3UMW7, Q09HN3
UniParc: UPI00005B290C, UPI00015DED47, UPI0000023B1D, UPI0000E13E9F
EMBL: AK144637, AK172578, AK151881, AK087496, BC031467, CH466560, AK172344, DQ899946, AL672070
Ensembl: ENSMUSG00000032577
KO: mmu:102626
Nucleutide sequences
EMBL-CDS: BAE30767.1, BAC39897.1, AAH31467.1, EDL21175.1, BAE25981.1, BAE42958.1, BAE43076.1, ABI64145.1
Ensembl_TRS: ENSMUST00000035194, ENSMUST00000192054
Protein sequencees
Ensembl_PRO: ENSMUSP00000035194, ENSMUSP00000141342
RefSeq: XP_006511682.1, XP_006511681.1, XP_006511680.1, NP_849238.1, NP_001303620.1, XP_036010401.1, XP_006511679.1
Others
UniRef100: UniRef100_Q3UMW7, UniRef100_Q09HN3
UniRef90: UniRef90_Q3UMW7-3, UniRef90_Q16644
UniRef50: UniRef50_Q16644, UniRef50_Q3UMW7-3
UniGene: Mm.222612, Mm.445242
CCDS: CCDS85722.1, CCDS23487.1

全选

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