| Type | Description |
|---|---|
| Definition | splicing factor 3b subunit 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:11:00 | Publicly available data from paired normal and tumor tissues in hepatocellular carcinoma (HCC) and results from patients with HCC suggest that SRSF3 and SF3B4 possess an inverse relationship. SRSF3 is a key molecule for determining SF3B4 levels in HCC cells | 32234894 |
| 2020-03-28 12:06:00 | A unique system comprising a p180-SF3b4-mRNA complex facilitates the selective assembly of polyribosomes on the endoplasmic reticulum. | 31004060 |
| 2019-04-06 11:02:00 | MiRNA-133b not only regulates the endogenous expression of SF3B4 but also modulates SF3B4-mediated AS efficiency in HCC tumorigenesis. | 30391496 |
| 2018-08-18 11:09:00 | SF3B4 indicates early-stage hepatocellular carcinoma in precancerous lesions, and also functions as an early-stage driver in the development of liver cancer. | 29397868 |
| 2017-10-21 12:53:00 | We identified two heterozygous frameshift mutations in the SF3B4 gene in three of the four fetuses investigated. The observed mutation was apparently de novo in one fetus for whom parental DNA was available. Thus, Acrofacial dysostosis syndrome of Rodriguez is an autosomal dominant condition and the recurrences identified in the initial report were likely due to gonadal mosaicism. | 27642715 |
| Type | IDs |
|---|---|
| Synonymous | AFD1, Hsh49, SAP49, SF3b49 |
| Gene |
UniProtKB-ID:
SF3B4_HUMAN,
B3KUJ0_HUMAN
UniprotKB:
Q15427,
B3KUJ0
UniParc:
UPI0000135472,
UPI000037327E
EMBL:
L35013,
CH471121,
BC090883,
BC004273,
AL590487,
AK097315,
AL591493,
BC013886
Ensembl:
ENSG00000143368
KO:
hsa:10262
|
| Nucleutide sequences |
EMBL-CDS:
AAH13886.1,
AAH90883.1,
AAH04273.1,
CAI12648.1,
AAA60300.1,
CAI12554.1,
EAW53595.1,
BAG53452.1
Ensembl_TRS:
ENST00000271628
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000271628
RefSeq:
NP_005841.1
|
| Others |
UniRef100:
UniRef100_B3KUJ0,
UniRef100_Q15427
UniRef90:
UniRef90_Q15427
UniRef50:
UniRef50_Q15427
UniGene:
Hs.516160
CCDS:
CCDS72900.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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