| Type | Description |
|---|---|
| Definition | connector enhancer of kinase suppressor of Ras 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:51:00 | knockdown of cnk, the CNKSR1 orthologue in Drosophila melanogaster brain, led to defects in eye and mushroom body (MB) structures. Findings support the possible role of CNKSR1 in brain development which can lead to cognitive impairment. | 30450701 |
| 2018-06-23 11:18:00 | CNKSR1 expression is increased in pancreatic cancer specimens and was found to be an independent prognostic marker of overall survival. | 28732488 |
| 2018-06-09 12:14:00 | Data indicate connector enhancer of kinase suppressor of Ras 1 protein (CNK1) as a molecular platform that controls c-raf protein (RAF) and c-akt protein (AKT) signalling and determines cell fate decisions in a cell type- and cell stage-dependent manner. | 27901111 |
| 2017-10-07 10:57:00 | The findings reveal SAM domain-dependent oligomerization by AKT as a switch for CNK1 activation. | 27769899 |
| 2015-12-19 10:23:00 | tyrosine phosphorylation is an important mechanism to control the subcellular localization of CNK1 and its distinct biological functions. | 26319181 |
| Type | IDs |
|---|---|
| Synonymous | CNK, CNK1 |
| Gene |
UniProtKB-ID:
CNKR1_HUMAN,
G3V160_HUMAN,
B4DL25_HUMAN,
Q53GM7_HUMAN
UniprotKB:
Q969H4,
G3V160,
B4DL25,
Q53GM7
UniParc:
UPI00017A7648,
UPI0000366501,
UPI0000070054,
UPI0000EE2ECA
EMBL:
BT006900,
CH471059,
AL391650,
AL355877,
BC011604,
AK222904,
AK296814,
BC012797,
AF100153
Ensembl:
ENSG00000142675
KO:
hsa:10256
|
| Nucleutide sequences |
EMBL-CDS:
AAC80558.1,
EAX07842.1,
AAH11604.1,
AAP35546.1,
AAH12797.1,
EAX07840.1,
BAG59387.1,
BAD96624.1,
EAX07841.1
Gene_ORFName:
hCG_40691,
hCG_40691
Ensembl_TRS:
ENST00000361530,
ENST00000374253,
ENST00000531191
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363371,
ENSP00000354609,
ENSP00000431817
RefSeq:
NP_001284576.1,
NP_006305.2,
NP_001284577.1
|
| Others |
UniRef100:
UniRef100_Q969H4,
UniRef100_Q969H4-2,
UniRef100_B4DL25
UniRef90:
UniRef90_B4DL25,
UniRef90_Q969H4
UniRef50:
UniRef50_B4DL25,
UniRef50_Q969H4
UniGene:
Hs.16232
CCDS:
CCDS276.1,
CCDS72732.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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