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10254 STAM2

10254

STAM2

signal transducing adaptor molecule 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition signal transducing adaptor molecule 2

研究结论

Date Results Publications
2020-11-21 13:12:00 Molecular recognition of ubiquitin and Lys63-linked diubiquitin by STAM2 UIM-SH3 dual domain: the effect of its linker length and flexibility. 31601934
2017-06-24 11:15:00 The authors propose a structural organization where the AMSH-SH3 binding motif interacts with the STAM2-SH3 domain and contributes to the correct positioning of AMSH prior to polyubiquitin chains' cleavage. 27725184
2016-08-27 12:50:00 The VHS domain of STAM2 directs AMSH to cleave longer Lys63-linked ubiquitin chains 26601948
2016-07-30 11:05:00 homologous domain of human Bro1 domain-containing proteins, Alix and Brox, binds CHMP4B but not STAM2, despite their high structural similarity 26866605
2014-06-28 10:31:00 correlation between the percentage of STAM2-positive cells and mitotic count was statistically significant in Gastrointestinal stromal tumors 24778033

名称对应

Type IDs
Synonymous Hbp, STAM2A, STAM2B
Gene
UniProtKB-ID: STAM2_HUMAN
UniprotKB: O75886
UniParc: UPI000015885D, UPI0000071984
EMBL: AF042274, CH471058, AF042273, AC079790, AL133600, BC028740, AK292265, AK292847
Ensembl: ENSG00000115145
KO: hsa:10254
Nucleutide sequences
EMBL-CDS: AAC63964.1, BAF85536.1, BAF84954.1, CAB63735.1, EAX11492.1, AAH28740.1, EAX11490.1, AAC63963.1, AAY14712.1
Ensembl_TRS: ENST00000263904
Protein sequencees
Ensembl_PRO: ENSP00000263904
RefSeq: NP_005834.4
Others
UniRef100: UniRef100_O75886
UniRef90: UniRef90_O75886
UniRef50: UniRef50_O75886
UniGene: Hs.17200
CCDS: CCDS2196.1

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