| Type | Description |
|---|---|
| Definition | sprouty RTK signaling antagonist 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:49:00 | Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells. | 32304210 |
| 2021-02-13 13:28:00 | Mechanism of SPRY1 methylation regulating natural aging of skin epidermal cells. | 31483543 |
| 2020-10-31 13:16:00 | MicroRNA-421 promotes inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis by targeting SPRY1. | 31646548 |
| 2020-06-20 12:01:00 | Sprouty1 is induced after weight loss in adipose stem/progenitor cells of formerly obese people acting as a negative regulator of MAPK signalling, which is necessary to properly trigger adipogenesis at early stages by a C/EBP beta dependent mechanism. | 31138786 |
| 2018-11-10 12:11:00 | Study demonstrated that Spry1 has a role in supporting mitogen-induced vascular hyperplasia, at least in part by promoting Akt/Rb signaling and increasing mitogen-induced cyclinD1 expression and decreasing p27Kip1 expression. | 29105817 |
| Type | IDs |
|---|---|
| Synonymous | hSPRY1 |
| Gene |
UniProtKB-ID:
SPY1_HUMAN
UniprotKB:
O43609
UniParc:
UPI0000035D8F
EMBL:
CH471056,
AF041037,
AY590694,
BC063856,
AY192146
Ensembl:
ENSG00000164056
KO:
hsa:10252
|
| Nucleutide sequences |
EMBL-CDS:
EAX05210.1,
AAT06102.1,
EAX05211.1,
EAX05209.1,
AAP20102.1,
AAH63856.1,
AAC39566.1
Ensembl_TRS:
ENST00000610581,
ENST00000651917,
ENST00000339241,
ENST00000394339,
ENST00000622283
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377871,
ENSP00000480540,
ENSP00000498292,
ENSP00000481675,
ENSP00000343785
RefSeq:
NP_005832.1,
NP_001362339.1,
NP_955359.1,
NP_001244967.1,
NP_001244968.1
|
| Others |
UniRef100:
UniRef100_O43609
UniRef90:
UniRef90_O43609
UniRef50:
UniRef50_O43609
UniGene:
Hs.744854
CCDS:
CCDS3731.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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