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10238 DCAF7

10238

DCAF7

DDB1 and CUL4 associated factor 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition DDB1 and CUL4 associated factor 7

研究结论

Date Results Publications
2020-05-30 11:21:00 DCAF7 is a novel regulator of ERCC1-XPF protein level and cellular nucleotide excision repair activity. 31493872
2019-04-27 10:56:00 DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B 30496304
2018-05-05 12:05:00 Immunoprecipitation and pulldown experiments identified DCAF7 as an adaptor for the association of the adenovirus E1A protein with DYRK1A and HIPK2 27307198
2017-05-27 10:52:00 knockdown of DCAF7 reduced the degradation of DNA ligase I in response to inhibition of proliferation and replacement of ubiquitylated lysine residues reduced the in vitro ubiquitylation of DNA ligase I by Cul4-DDB1 and DCAF7. In contrast, a different E3 ubiquitin ligase regulates FEN-1 turnover. 27573245
2015-02-14 10:04:00 results demonstrate that the molecular chaperone TRiC/CCT is essential for correct protein folding, DYRK1A binding, and nuclear accumulation of WDR68. 25342745

名称对应

Type IDs
Synonymous AN11, HAN11, SWAN-1, WDR68
Gene
UniProtKB-ID: DCAF7_HUMAN
UniprotKB: P61962
UniParc: UPI0000004087, UPI00017A838F
EMBL: AK303212, BC001264, AC113554, CH471109, U94747
Ensembl: ENSG00000136485
KO: hsa:10238
Nucleutide sequences
EMBL-CDS: AAC18913.1, EAW94306.1, AAH01264.1, BAG64301.1, EAW94305.1
Ensembl_TRS: ENST00000614556, ENST00000415273, ENST00000431926
Protein sequencees
Ensembl_PRO: ENSP00000402312, ENSP00000403920, ENSP00000483236
RefSeq: NP_005819.3
Others
UniRef100: UniRef100_P61962
UniRef90: UniRef90_P61962
UniRef50: UniRef50_P61962
UniGene: Hs.410596
CCDS: CCDS74127.1

全选

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