| Type | Description |
|---|---|
| Definition | glycerol-3-phosphate acyltransferase 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 11:47:00 | glycerolipid synthesis is induced during macrophage activation. GPAT4 protein level and GPAT3/GPAT4 enzymatic activity increase during this process, and these two isoforms were required for the accumulation of cell TAG and PL. | 30523059 |
| 2017-11-26 00:16:00 | These data identify SEIPIN as an evolutionarily conserved regulator of microsomal GPAT. | 27806294 |
| 2015-09-12 11:41:00 | GPAT4 limits excessive fatty acid oxidation and the detrimental induction of a hypermetabolic state | 25918168 |
| 2014-09-27 12:18:00 | Data (from studies in knockout mice) suggest GPAT4-derived phosphatidic acid impairs insulin signaling in liver/contributes to insulin resistance via interaction of mTOR (mechanistic target of rapamycin)/Rictor (RPTOR independent companion of mTOR). | 24939733 |
| 2013-11-30 10:47:00 | GPAT1, but not GPAT4, is required to incorporate de novo synthesized fatty acids into TAG and to divert them away from oxidation. | 23908354 |
| Type | IDs |
|---|---|
| Synonymous | AU041707, AW545732, Agpat6, Tsarg7 |
| Gene |
UniProtKB-ID:
GPAT4_MOUSE
UniprotKB:
Q8K2C8
UniParc:
UPI00000E8856
EMBL:
AY489184,
AK077561,
AK083589,
AF406611,
AK045235,
AK161270,
AK169257,
BC031767
Ensembl:
ENSMUSG00000031545
KO:
mmu:102247
|
| Nucleutide sequences |
EMBL-CDS:
BAC38962.1,
BAC36864.1,
BAE41020.1,
AAH31767.1,
BAE36282.1,
AAP97283.1,
AAS75838.1,
BAC32273.1
Ensembl_TRS:
ENSMUST00000167004
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000127325
RefSeq:
NP_061213.2,
XP_011240406.1
|
| Others |
UniRef100:
UniRef100_Q8K2C8
UniRef90:
UniRef90_Q8K2C8
UniRef50:
UniRef50_Q8K2C8
UniGene:
Mm.200898
CCDS:
CCDS22189.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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