| Type | Description |
|---|---|
| Definition | angiopoietin like 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:06:00 | Angiopoietin-like protein 7 mediates TNF-alpha-induced adhesion and oxidative stress in human umbilical vein epithelial cell. | 32525822 |
| 2020-08-01 15:19:00 | A rare missense variant in ANGPTL7 with glaucoma protective effect supports inhibition or down-regulation of ANGPTL7 as a therapeutic strategy for glaucoma. | 32369491 |
| 2020-05-16 10:14:00 | Downregulation of ANGPTL7 reversed AngII-induced cell proliferation and cell inflammation and promoted apoptosis in AngII-induced VSMC cells. Therefore, ANGPTL7 can be a potential target in AngII-induced hypertension. | 31302653 |
| 2017-09-02 11:01:00 | obesity increases the level of ANGPTL7 in both plasma and adipose tissue. Increased expression of ANGPTL7 might play a minor role in the regulation of TG level in obese subjects either directly or through interaction with other ANGPTL protein members. Physical exercise reduced the level of ANGPTL7 highlighting the potential for targeting this protein as a therapeutic target for regulating dyslipidemia. | 28264047 |
| 2016-01-16 11:22:00 | ANGPTL7, which is abundantly expressed in keratocytes, plays a major role in maintaining corneal avascularity and transparency. | 25622036 |
| Type | IDs |
|---|---|
| Synonymous | AngX, CDT6, dJ647M16.1 |
| Gene |
UniProtKB-ID:
ANGL7_HUMAN
UniprotKB:
O43827
UniParc:
UPI0000035976
EMBL:
AB593026,
CH471130,
AL391561,
BT009802,
AL049653,
BC001881,
AY358301,
DQ012507,
AB593027,
AK313716,
AJ300188,
Y16132
Ensembl:
ENSG00000171819
KO:
hsa:10218
|
| Nucleutide sequences |
EMBL-CDS:
AAY22173.1,
CAC15571.1,
AAH01881.1,
BAG36459.1,
EAW71685.1,
AAP88804.1,
BAJ83980.1,
BAJ83981.1,
CAA76078.1,
AAQ88668.1
Gene_ORFName:
UNQ313/PRO356
Ensembl_TRS:
ENST00000376819
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366015
RefSeq:
NP_066969.1,
XP_016855493.1
|
| Others |
UniRef100:
UniRef100_O43827
UniRef90:
UniRef90_O43827
UniRef50:
UniRef50_O43827
UniGene:
Hs.146559
CCDS:
CCDS128.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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