| Type | Description |
|---|---|
| Definition | proteasome 26S subunit, non-ATPase 14 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:22:00 | Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization. | 33154524 |
| 2021-02-13 13:29:00 | The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport. | 32210007 |
| 2020-07-04 10:49:00 | PSMD14 was significantly upregulated in hepatocellular carcinoma (HCC) tissues. Overexpression of PSMD14 correlated with vascular invasion, tumor number, tumor recurrence, and poor tumor-free and overall survival of patients with HCC. Mechanistically, study identified PSMD14 as a novel post-translational regulator of GRB2.PSMD14 inhibits degradation of GRB2 via deubiquitinating this oncoprotein in HCC cells. | 31634528 |
| 2020-04-04 10:05:00 | These findings suggest that the PSMD14-ALK2 axis plays an essential role in initiation of the BMP6 signaling pathway and contributes to tumorigenesis and chemoresistance of colorectal cancers. | 31685442 |
| 2020-01-25 14:17:00 | POH1 was overexpressed in prostate cancer and was correlated with pathological grades in human prostate cancers. | 31212367 |
| Type | IDs |
|---|---|
| Synonymous | PAD1, POH1, RPN11 |
| Gene |
UniProtKB-ID:
PSDE_HUMAN,
A0A140VKF2_HUMAN
UniprotKB:
O00487,
A0A140VKF2
UniParc:
UPI0000027819
EMBL:
HM005692,
U86782,
CH471058,
AK055128,
BC066336
Ensembl:
ENSG00000115233
KO:
hsa:10213
|
| Nucleutide sequences |
EMBL-CDS:
BAG51474.1,
AAC51866.1,
AAH66336.1,
EAX11370.1,
AEE61289.1
Ensembl_TRS:
ENST00000409682
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386541
RefSeq:
NP_005796.1
|
| Others |
UniRef100:
UniRef100_O00487
UniRef90:
UniRef90_O00487
UniRef50:
UniRef50_O00487
UniGene:
Hs.740477
CCDS:
CCDS46437.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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