| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:57:00 | These data directly implicate translational repression in C9orf72 repeat-induced neurodegeneration and identify eIF1A as a novel modifier of C9orf72 repeat toxicity. | 30604225 |
| 2019-07-20 10:57:00 | results indicate that in humans, eIF5B displacing eIF2 from upon subunit joining may be coupled to eIF1A displacing eIF5 from eIF5B, allowing the eIF5:eIF2-GDP complex to leave the ribosome. | 30211544 |
| 2019-06-29 10:50:00 | We report that eIF4G1 exists in two complexes, either with eIF4E or with eIF1. Using an eIF1 mutant impaired in eIF4G1 binding, we demonstrate that eIF1-eIF4G1 interaction is important for leaky scanning and for avoiding m7G-cap-proximal initiation. | 29987188 |
| 2017-02-04 10:40:00 | Anti-Sui1 could be utilized as a supplementary serological marker. | 26386724 |
| 2016-04-09 10:04:00 | eIF1A is a novel component of the Ago2-centred RNA-induced silencing complexes (RISCs) and augments Ago2-dependent and miRNA biogenesis. | 26018492 |
| Type | IDs |
|---|---|
| Synonymous | A121, EIF-1, EIF1A, ISO1, SUI1 |
| Gene |
UniProtKB-ID:
EIF1_HUMAN,
Q6IAV3_HUMAN
UniprotKB:
P41567,
Q6IAV3
UniParc:
UPI000000DC99
EMBL:
AJ012375,
CH471152,
BT006645,
BC008710,
L26247,
CR457051,
AK311862,
AF100737,
BC005118,
AF083441
Ensembl:
ENSG00000173812
KO:
hsa:10209
|
| Nucleutide sequences |
EMBL-CDS:
AAA60602.1,
AAH08710.1,
AAD52028.1,
AAD19900.1,
AAH05118.1,
EAW60754.1,
CAD66615.1,
AAP35291.1,
CAG33332.1,
BAG34803.1
Gene_ORFName:
hCG_1771529
Ensembl_TRS:
ENST00000469257
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000419449
RefSeq:
NP_005792.1
|
| Others |
UniRef100:
UniRef100_P41567
UniRef90:
UniRef90_P41567
UniRef50:
UniRef50_P41567
UniGene:
Hs.150580
CCDS:
CCDS11403.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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