| Type | Description |
|---|---|
| Definition | myelin protein zero like 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:30:00 | Epithelial V-like antigen 1 (EVA1) expression is increased in hepatocellular carcinoma (HCC) and is associated with a poor prognosis and recurrence in HCC patients. Overexpression of EVA1 promotes cell growth, invasion and migration in vitro. EVA1 is able to upregulate the expression of genes in the ERBB3-PI3K pathway. An increased level of AKT phosphorylation is detected in HCC cells after EVA1 overexpression. | 31997489 |
| 2019-03-30 11:53:00 | We show that Mpzl2 is expressed in mouse inner ear, and the protein localizes in the auditory inner and outer hair cells, with an asymmetric subcellular localization. We thus present MPZL2 as a novel gene associated with sensorineural hearing loss. | 29982980 |
| 2016-07-30 11:46:00 | CLCA2 links junctional adhesion molecule EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation. | 26930581 |
| 2016-06-11 10:18:00 | Findings highlight Eva1 as a novel regulator of GIC function and also provide new mechanistic insight into the role of noncanonical NF-kappaB activation in GIC. | 26677976 |
| 2011-08-20 10:49:00 | EVA is expressed in human choroid plexus epithelial cells and CD4 T lymphocytes and regulates CD4+ T lymphocyte adhesion to human choroid plexus epithelial cells in vitro. These data suggest a novel mechanism to regulate CNS immune surveillance. | 21440040 |
| Type | IDs |
|---|---|
| Synonymous | DFNB111, EVA, EVA1 |
| Gene |
UniProtKB-ID:
MPZL2_HUMAN,
A0A024R3K1_HUMAN
UniprotKB:
O60487,
A0A024R3K1
UniParc:
UPI000004781C
EMBL:
AF030455,
AF275945,
AY359061,
AK290326,
BC017774,
CH471065,
AF304447
Ensembl:
ENSG00000149573
KO:
hsa:10205
|
| Nucleutide sequences |
EMBL-CDS:
BAF83015.1,
AAH17774.1,
AAG23183.1,
AAF87240.1,
EAW67358.1,
AAQ89420.1,
AAC39762.1,
EAW67359.1
Gene_ORFName:
UNQ606/PRO1192,
hCG_41148
Ensembl_TRS:
ENST00000438295,
ENST00000278937
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000408362,
ENSP00000278937
RefSeq:
NP_658911.1,
NP_005788.1
|
| Others |
UniRef100:
UniRef100_O60487
UniRef90:
UniRef90_O60487
UniRef50:
UniRef50_O60487
UniGene:
Hs.116651
CCDS:
CCDS8393.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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