例如:"NBL1", "4681", "drought"
收藏
10203 CALCRL

10203

CALCRL

calcitonin receptor like receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition calcitonin receptor like receptor

研究结论

Date Results Publications
2021-02-02 13:22:00 Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells. 33462236
2020-08-01 14:37:00 AM2 signaling is suppressed in adipose tissue in obesity, involving lower receptor expression and ligand availability, likely contributing to insulin resistance and other aspects of the pathophysiology associated with obesity. 31642491
2020-05-30 13:04:00 CRISPR-Cas9-mediated knockout of CALCRL significantly impaired colony formation in human myeloid leukemia cell lines. Overall, our study demonstrates that CALCRL predicts outcome beyond existing risk factors and is a potential therapeutic target in AML. 31182782
2019-09-07 11:17:00 hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. 30115739
2019-03-23 11:33:00 structure of the human CGRP receptor in complex with CGRP and the Gs-protein heterotrimer at 3.3 A global resolution, determined by Volta phase-plate cryo-electron microscopy 30209400

名称对应

Type IDs
Synonymous CGRPR, CRLR
Gene
UniProtKB-ID: CALRL_HUMAN, D3DPG9_HUMAN
UniprotKB: Q16602, D3DPG9
UniParc: UPI000013D4CD, UPI0000D4B16E
EMBL: CH471058, L76380, AC007319, AK292998, U17473, AC074020, AY389506, AK291630
Ensembl: ENSG00000064989
KO: hsa:10203
Nucleutide sequences
EMBL-CDS: BAF85687.1, AAQ91332.1, AAA62158.1, AAY14806.1, AAC41994.1, BAF84319.1, AAY14996.1, EAX10926.1, EAX10925.1
Gene_ORFName: hCG_22606
Ensembl_TRS: ENST00000410068, ENST00000409998, ENST00000392370
Protein sequencees
Ensembl_PRO: ENSP00000376177, ENSP00000387190, ENSP00000386972
RefSeq: NP_005786.1, NP_001356364.1, NP_001258680.1, XP_005246291.2, NP_001356363.1, XP_005246289.2
Others
UniRef100: UniRef100_D3DPG9, UniRef100_Q16602
UniRef90: UniRef90_Q16602
UniRef50: UniRef50_Q16602
UniGene: Hs.470882, Hs.744587
CCDS: CCDS2293.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员