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10202 DHRS2

10202

DHRS2

dehydrogenase/reductase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition dehydrogenase/reductase 2

研究结论

Date Results Publications
2020-04-18 12:26:00 DHRS2 is dispensable for up-regulation of romidepsin effectors. 30460772
2020-03-28 10:41:00 Results show that DHRS2 is highly expressed in oxaliplatin-resistant colorectal cancer (CRC) cell line. Furthermore, DHRS2 regulates ERCC1 to promote oxaliplatin resistance through a p53dependent pathway, and mediates EMT by suppressing Ecadherin expression. 31436301
2019-12-21 12:01:00 Our report suggests that activating DHRS2 to reprogram lipid homeostasis may be a target for the development of targeted therapies against NPC. 31291971
2019-04-06 10:31:00 Among these targets, dehydrogenase/reductase member 2 DHRS2 and MYO1B were directly regulated by miR1453p in esophageal squamous cell carcinoma (ESCC) cells by dual luciferase reporter assays. Aberrantly expressed DHRS2 and MYOIB were detected in ESCC clinical specimens, and their overexpression enhanced cancer cell aggressiveness. 30535463
2019-03-09 11:07:00 Low DHRS2 expression promotes esophageal squamous cell carcinoma. 29106393

名称对应

Type IDs
Synonymous HEP27, SDR25C1
Gene
UniProtKB-ID: DHRS2_HUMAN
UniprotKB: Q13268
UniParc: UPI00001A3E34, UPI000004C787
EMBL: CH471078, AK222857, AF244132, U31875, BC002786, AL135999, BC007339
Ensembl: ENSG00000100867
KO: hsa:10202
Nucleutide sequences
EMBL-CDS: EAW66130.1, AAH07339.2, EAW66131.1, AAA82048.1, BAD96577.1, AAG33703.1, AAH02786.1
Ensembl_TRS: ENST00000250383, ENST00000344777, ENST00000611765
Protein sequencees
Ensembl_PRO: ENSP00000344674, ENSP00000481607, ENSP00000250383
RefSeq: NP_005785.1, XP_005267306.1, NP_878912.1, XP_011534640.1, XP_011534641.1, NP_001305764.1, XP_006720064.1
Others
UniRef100: UniRef100_Q13268
UniRef90: UniRef90_Q13268
UniRef50: UniRef50_Q9BTZ2
UniGene: Hs.272499
CCDS: CCDS41927.1, CCDS9604.1

全选

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