| Type | Description |
|---|---|
| Definition | ALG3 alpha-1,3- mannosyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:30:00 | ALG3 contributes to the malignancy of non-small cell lung cancer and is negatively regulated by MiR-98-5p. | 31899049 |
| 2020-03-21 10:36:00 | Study adds four new biochemically confirmed variants to the list of ALG3-congenital disorder of glycosylation (CDG) inducing variants: c.350G>C (p.R117P), c.1263G>A (p.W421*), c.1037A>G (p.N346S), and the intron variant c.296+4A>G. Furthermore, an additional open-reading frame of 141 bp (AAGRP) in the coding region of ALG3 was identified. | 31067009 |
| 2020-01-11 11:50:00 | We found that PPFIA1 and ALG3 were distinctively overexpressed at the mRNA level in HNSCC tissues compared with normal tissues, they had a significant co-occurrence relationship. Patients without both PPFIA1 and ALG3 mRNA expression alterations had better overall survival and disease/progression-free survival compared with patients with both PPFIA1 and ALG3 alterations. | 30805892 |
| 2019-02-16 11:15:00 | our data suggest the involvement of hNOT-1/ALG3-1 in various molecular contexts determining essential processes associated with distinct cellular machineries and related to various pathologies, such as cancer, viral infections, neuronal and immunological disorders and Congenital Disorders of Glycosylation. | 29547901 |
| 2018-10-06 12:08:00 | Silencing ALG3 or HSF2 inhibited the proliferation, migration, and invasion abilities of MCF-7 cells. | 29799832 |
| Type | IDs |
|---|---|
| Synonymous | CDG1D, CDGS4, CDGS6, D16Ertd36e, NOT56L, Not56, not |
| Gene |
UniProtKB-ID:
ALG3_HUMAN,
C9J7S5_HUMAN
UniprotKB:
Q92685,
C9J7S5
UniParc:
UPI0000125838,
UPI000020A8BD,
UPI000046D374
EMBL:
BC002839,
BC004313,
AC061705,
AK289361,
Y09022
Ensembl:
ENSG00000214160
KO:
hsa:10195
|
| Nucleutide sequences |
EMBL-CDS:
CAA70220.1,
AAH02839.1,
BAF82050.1,
AAH04313.1
Ensembl_TRS:
ENST00000397676,
ENST00000445626,
ENST00000455059
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380793,
ENSP00000402744,
ENSP00000397613
RefSeq:
XP_011510624.1,
XP_024309064.1,
XP_011510625.1,
NP_001006942.1,
NP_005778.1
|
| Others |
UniRef100:
UniRef100_Q92685,
UniRef100_C9J7S5
UniRef90:
UniRef90_Q92685,
UniRef90_I3LQI7
UniRef50:
UniRef50_Q92685-2,
UniRef50_Q92685
UniGene:
Hs.478481
CCDS:
CCDS46967.1,
CCDS46968.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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