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10193 RNF41

10193

RNF41

ring finger protein 41

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 41

研究结论

Date Results Publications
2019-02-02 11:22:00 Low HER3 expression is suggested to be a valuable prognostic biomarker to predict recurrence in HER2-amplified breast cancer. 30367623
2019-02-02 10:57:00 RNF41 is essential to IFNI pathway activation in order to maintain muscle insulin sensitivity during human obesity. 29410345
2018-05-26 10:45:00 Data (including data from studies using knockout and transgenic mice/cells) suggest that CLEC16A, NRDP1, and USP8 form tripartite complex; CLEC16A-NRDP1-USP8 complex appears to rely on ubiquitin signals to promote mitophagy and maintain mitochondrial function necessary for beta-cell function. (CLEC16A = C-type lectin domain family 16 member A; NRDP1 = ubiquitin-protein ligase NRDP1; USP8 = ubiquitin specific peptidase 8) 29180353
2018-03-03 10:55:00 Over-expression of miR-497 promotes the proliferation of glioma cells U87 by targeting Nrdp1. 28871945
2017-10-14 12:59:00 Authors conclude that the planar cell polarity (PCP) pathway contributes significantly to the motility and hence the invasiveness of glioblastoma multiforme (GBM) cells, and that Nrdp1 acts as a negative regulator of PCP signaling by inhibiting Dvl through a novel polyubiquitination mechanism. 28481871

名称对应

Type IDs
Synonymous FLRF, NRDP1, SBBI03
Gene
UniProtKB-ID: RNF41_HUMAN, A0A024RB33_HUMAN
UniprotKB: Q9H4P4, A0A024RB33
UniParc: UPI00001D6A04, UPI000006F47F
EMBL: AF077599, AC073896, CH471054, BC024284, AY007109, BC032637, AK314811
Ensembl: ENSG00000181852
KO: hsa:10193
Nucleutide sequences
EMBL-CDS: BAG37335.1, AAC27647.1, EAW96910.1, EAW96909.1, AAG01988.1, AAH32637.1, EAW96911.1
Gene_ORFName: SBBI03, hCG_24978
Ensembl_TRS: ENST00000394013, ENST00000552656, ENST00000615206, ENST00000345093
Protein sequencees
Ensembl_PRO: ENSP00000377581, ENSP00000484671, ENSP00000447303, ENSP00000342755
RefSeq: NP_005776.1, XP_011536036.1, NP_001229755.1, XP_011536037.1, XP_005268618.1, NP_919339.1, NP_919340.1
Others
UniRef100: UniRef100_Q9H4P4
UniRef90: UniRef90_Q9H4P4
UniRef50: UniRef50_Q9H4P4
UniGene: Hs.524502
CCDS: CCDS8909.1, CCDS8910.1

全选

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