| Type | Description |
|---|---|
| Definition | cyclin dependent kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study. | 33794206 |
| 2021-04-13 10:13:00 | HMGB1 is a key factor for tamoxifen resistance and has the potential to predict the efficacy of CDK4/6 inhibitors in breast cancer. | 33453094 |
| 2021-04-03 13:31:00 | Prx II reduces oxidative stress and cell senescence in chondrocytes by activating the p16-CDK4/6-pRb-E2F signaling pathway. | 32329817 |
| 2021-04-03 13:28:00 | KLF5 promotes proliferation in gastric cancer via regulating p21 and CDK4. | 32373958 |
| 2021-03-27 14:44:00 | CDK4/6 regulate lysosome biogenesis through TFEB/TFE3. | 32662822 |
| Type | IDs |
|---|---|
| Synonymous | CMM3, PSK-J3 |
| Gene |
UniProtKB-ID:
CDK4_HUMAN,
A0A024RBB6_HUMAN
UniprotKB:
P11802,
A0A024RBB6
UniParc:
UPI0000113582,
UPI00017A7814
EMBL:
AK297901,
BC003644,
CH471054,
M14505,
S67448,
AF507942,
AC025165,
U37022,
CR407668,
BC005864,
AK313701,
U81031,
BC010153,
CR542247,
Z48970
Ensembl:
ENSG00000135446
KO:
hsa:1019
|
| Nucleutide sequences |
EMBL-CDS:
AAH10153.1,
EAW97058.1,
BAG36447.1,
AAD13991.1,
CAA88834.1,
AAC50506.1,
AAA35673.1,
BAG60221.1,
CAG28596.1,
AAM23014.1,
CAG47043.1,
AAH05864.1,
AAH03644.1,
AAC39521.2,
EAW97060.1
Gene_ORFName:
hCG_40151
Ensembl_TRS:
ENST00000257904
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257904
RefSeq:
NP_000066.1
|
| Others |
UniRef100:
UniRef100_P11802
UniRef90:
UniRef90_P11802
UniRef50:
UniRef50_P11802
UniGene:
Hs.95577
CCDS:
CCDS8953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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