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1018 CDK3

1018

CDK3

cyclin dependent kinase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin dependent kinase 3

研究结论

Date Results Publications
2018-10-27 10:29:00 These results suggest that miR-125a-3p can function as a novel tumor suppressor in ER(+) breast cancer by targeting CDK3, which may be a potential therapeutic approach for TamR breast cancer therapy 28939591
2018-09-01 11:29:00 HuR facilitated lung cancer stemness dependent on CDK3 expression. miR-873 or miR-125a-3p level was negatively correlated with HuR and CDK3 expression levels in lung cancer tissues. HuR facilitates lung cancer stemness via regulating miR-873/CDK3 and miR-125a-3p/CDK3 axis. 29344850
2018-03-24 11:00:00 ectopic expression of HuR promotes breast cancer cell proliferation and survival by directly binding to and stabilizing CDK3 mRNA. 28501005
2017-09-16 11:21:00 These results provided evidence supporting the oncogenic potential of NFAT3 and suggested that CDK3-mediated phosphorylation of NFAT3 has an important role in skin tumorigenesis. 27893713
2017-08-12 11:05:00 The analysis of tumor and matched normal lung tissues indicates that miR-150 downregulation in lung tumors correlates with higher CDK3 levels. In addition, miR-150 transfection experiments with cancer-derived cell lines reveal that miR-150-mediated CDK3 suppression directly induces growth inhibition. 28108217

名称对应

Type IDs
Gene
UniProtKB-ID: CDK3_HUMAN
UniprotKB: Q00526
UniParc: UPI0000113587
EMBL: AY789470, X66357
Ensembl: ENSG00000250506
KO: hsa:1018
Nucleutide sequences
EMBL-CDS: AAV40830.1, CAA47001.1
Ensembl_TRS: ENST00000448471, ENST00000425876
Protein sequencees
Ensembl_PRO: ENSP00000400088, ENSP00000410561
RefSeq: NP_001249.1
Others
UniRef100: UniRef100_Q00526
UniRef90: UniRef90_Q00526
UniRef50: UniRef50_P97377
UniGene: Hs.706766
CCDS: CCDS11736.1

全选

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研究热度

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