| Type | Description |
|---|---|
| Definition | RNA binding motif protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 10:46:00 | interfering with the axis of RBM7 and P-TEFb provokes cellular hypersensitivity to DNA-damage-inducing agents due to activation of apoptosis. Our work uncovers the importance of stress-dependent stimulation of Pol II pause release, which enables a pro-survival transcriptional response that is crucial for cell fate upon genotoxic insult. | 30824372 |
| 2018-09-08 11:44:00 | a proline-rich segment of ZCCHC8 as the interaction site for the RNA-recognition motif (RRM) of RBM7 and present the crystal structure of the corresponding complex at 2.0 A resolution. | 27905398 |
| 2017-07-22 10:57:00 | Knock-down of rbm7, exosc8 and exosc3 in zebrafish showed a common pattern of defects in motor neurons and cerebellum. Our data indicate that impaired RNA metabolism may underlie the clinical phenotype by fine tuning gene expression which is essential for correct neuronal differentiation | 27193168 |
| 2017-04-15 10:10:00 | RBM8 and CBP20 RRM-domain crystal structures were used to successfully determine the RBM7 structure by molecular replacement. The structure reveals a ring-shaped pentameric assembly, which is most likely a consequence of crystal packing | 27139832 |
| 2015-03-28 13:15:00 | Phosphorylation of RBM7 by the p38(MAPK)/MK2 axis increases nuclear ncRNA stability by blocking their RBM7-binding and subsequent RNA exosome targeting to allow stress-dependent modulations of the noncoding transcriptome. | 25525152 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RBM7_HUMAN,
G3V1T9_HUMAN,
J3KPD3_HUMAN
UniprotKB:
Q9Y580,
G3V1T9,
J3KPD3
UniParc:
UPI000013337E,
UPI00001FA3CC,
UPI0000EE39CF
EMBL:
CH471065,
AP002373,
AK312619,
BC034381,
AK002015,
AF156098
Ensembl:
ENSG00000076053
KO:
hsa:10179
|
| Nucleutide sequences |
EMBL-CDS:
EAW67247.1,
BAG35505.1,
AAH34381.1,
AAD39257.1,
BAA92036.1,
EAW67246.1,
EAW67248.1
Gene_ORFName:
hCG_2032547,
hCG_2032547
Ensembl_TRS:
ENST00000540163,
ENST00000545678,
ENST00000375490
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439918,
ENSP00000445848,
ENSP00000364639
RefSeq:
NP_057174.1,
NP_001272977.1,
NP_001272974.1,
NP_001272976.1,
NP_001272975.1
|
| Others |
UniRef100:
UniRef100_J3KPD3,
UniRef100_Q9Y580
UniRef90:
UniRef90_Q9Y580
UniRef50:
UniRef50_Q9Y580
UniGene:
Hs.7527
CCDS:
CCDS8370.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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