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10178 TENM1

10178

TENM1

teneurin transmembrane protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition teneurin transmembrane protein 1

研究结论

Date Results Publications
2020-12-19 13:41:00 MicroRNA-486 inhibits cell proliferation, invasion and migration via down-regulating the TENM1 expressions and affecting ERK and Akt signaling pathways and epithelial-to-mesenchymal transition in papillary thyroid carcinoma. 31646573
2018-06-09 11:04:00 Taken together, the results indicate that distinct pathways are involved in papillary thyroid cancer progression, and TENM1 is a potential marker of cancer progression. 28004221
2017-09-02 10:20:00 ODZ1, a protein that participates in the embryonic development of the brain, is also involved in cancer progression by promoting the growth and invasion capabilities of GSCs via a transcriptional pathway that induces the expression of RhoA and activation of downstream ROCK. 27641332
2017-07-01 11:37:00 Results of our study, that describes a new Tenm1 mouse, agree with the hypothesis that TENM1 has a role in olfaction. However, additional studies should be done in larger Congenital general anosmia (CGA) cohorts, to provide statistical evidence that loss-of-function mutations in TENM1 can solely cause the disease in our and other CGA cases 27040985
2016-09-10 11:03:00 Data suggest teneurin-1/TENM1 (and possibly TENM3) undergoes proteolysis to TCAPs (teneurin C-terminal associated peptides) that form intercellular adhesive units with latrophilin; signaling via TENM1 TCAPs appears to regulate reproduction. [REVIEW] 26485751

名称对应

Type IDs
Synonymous ODZ1, ODZ3, TEN-M1, TNM, TNM1, ten-1
Gene
UniProtKB-ID: TEN1_HUMAN, B7ZMH4_HUMAN
UniprotKB: Q9UKZ4, B7ZMH4
UniParc: UPI000189A92F, UPI0000211B6A, UPI0000050EDD
EMBL: AF100772, AL031075, Z81008, BC140783, AL022718, Z83823, BC144543, AL023878, Z85995
Ensembl: ENSG00000009694
KO: hsa:10178
Nucleutide sequences
EMBL-CDS: AAF04723.1, AAI40784.1, AAI44544.1
Ensembl_TRS: ENST00000422452, ENST00000371130
Protein sequencees
Ensembl_PRO: ENSP00000360171, ENSP00000403954
RefSeq: XP_016884699.1, XP_016884697.1, XP_016884705.1, NP_001156751.1, XP_016884700.1, XP_016884702.1, NP_001156750.1, XP_016884701.1, XP_016884698.1, NP_055068.2, XP_016884703.1, XP_016884704.1, XP_011529539.1, XP_011529532.1, XP_011529538.2
Others
UniRef100: UniRef100_B7ZMH4, UniRef100_Q9UKZ4
UniRef90: UniRef90_Q9W6V6
UniRef50: UniRef50_Q9W6V6
UniGene: Hs.23796, Hs.744536
CCDS: CCDS55488.1, CCDS14609.1

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研究热度

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