| Type | Description |
|---|---|
| Definition | sorbin and SH3 domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 10:17:00 | Vinexin beta deficiency attenuates atherogenesis primarily by suppressing vascular inflammation and inactivating Akt-nuclear factor kappaB signaling. Our data suggest that vinexin beta could be a therapeutic target for the treatment of atherosclerosis. | 28209562 |
| 2017-08-05 12:47:00 | The chromosome 8p tumor suppressor genes SORBS3 and SH2D4A are physically and functionally linked and provide a molecular mechanism of inhibiting IL-6 signaling in hepatocellular carcinoma cells. | 27311882 |
| 2016-12-17 10:50:00 | Study identified possible epigenetic influence on differential gene expression in SORBS3 under obese conditions. | 27437034 |
| 2015-09-26 21:44:00 | Our findings revealed that Vinexin-beta acts as a novel modulator of ischaemic injury | 25824575 |
| 2015-09-05 10:24:00 | Taken together, the findings suggest that vinexin beta modulates NS5A phosphorylation via its interaction with NS5A, thereby regulating hepatitis C virus replication, implicating vinexin beta in the viral life cycle. | 25972535 |
| Type | IDs |
|---|---|
| Synonymous | SCAM-1, SCAM1, SH3D4 |
| Gene |
UniProtKB-ID:
VINEX_HUMAN
UniprotKB:
O60504
UniParc:
UPI00001AE6B5,
UPI000007328E
EMBL:
AF064807,
BC067260,
CH471080,
BC091514,
BC010146,
AC037459,
AF037261
Ensembl:
ENSG00000120896
KO:
hsa:10174
|
| Nucleutide sequences |
EMBL-CDS:
AAD32304.1,
AAH10146.1,
AAH91514.1,
EAW63675.1,
AAC09244.1,
AAH67260.2
Ensembl_TRS:
ENST00000240123,
ENST00000523965
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000240123,
ENSP00000429764
RefSeq:
XP_016868435.1,
XP_006716329.1,
NP_001018003.1,
XP_005273428.1,
XP_016868433.1,
NP_005766.3,
XP_016868434.1
|
| Others |
UniRef100:
UniRef100_O60504
UniRef90:
UniRef90_O60504
UniRef50:
UniRef50_O60504
UniGene:
Hs.528572
CCDS:
CCDS6031.1,
CCDS47824.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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