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10164 CHST4

10164

CHST4

carbohydrate sulfotransferase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition carbohydrate sulfotransferase 4

研究结论

Date Results Publications
2019-03-09 11:55:00 mRNA transcript analyses on the genes involved in synthesizing GlcNAc-6-O-sulfated glycans in human colon cancer tissues indicated that GlcNAc6ST-2 (CHST4) is preferentially expressed in cancer cells ... GlcNAc6ST-3 (CHST5) was only expressed in nonmalignant epithelial cells, whereas GlcNAc6ST-1 (CHST2) was expressed equally in both cancerous and nonmalignant epithelial cells. 30093410
2017-06-24 10:15:00 Data suggest that GlcNAc6ST-2 (CHST4) is critical for biosynthesis of MECA-79 sulfated glycans in apical membranes of small-sized intrahepatic bile ducts and of cholangiolocellular carcinoma (CoCC) cells; MUC1 protein decorated with GlcNAc6ST-2-dependent MECA-79 sulfated glycans may serve as a useful CoCC marker. 27748735
2015-04-18 11:20:00 A method for O-GlcNAc detection using in vitro sulfation with two N-acetylglucosamine (GlcNAc)-specific sulfotransferases, carbohydrate sulfotransferase 2 and carbohydrate sulfotransferase 4. 24799377
2010-03-15 11:28:00 GlcNAc6ST2 could therefore be a good serological marker for detecting early-stage uterine cervical and corpus cancers. 19156517
2010-01-21 00:00:00 N-acetylgluosamine-6-O-sulfotransferase is overexpressed in a subgroup of paediatric precursor-B acute lymphoblastic leukaemia 16386360

名称对应

Type IDs
Synonymous GST3, GlcNAc6ST2, HECGLCNAC6ST, LSST
Gene
UniProtKB-ID: CHST4_HUMAN
UniprotKB: Q8NCG5
UniParc: UPI000006F41D
EMBL: BC035282, AK074746, AF149783, AF131235, AF280088
Ensembl: ENSG00000140835
KO: hsa:10164
Nucleutide sequences
EMBL-CDS: AAK48417.1, BAC11177.1, AAD33015.1, AAG48246.1, AAH35282.1
Ensembl_TRS: ENST00000539698, ENST00000338482
Protein sequencees
Ensembl_PRO: ENSP00000341206, ENSP00000441204
RefSeq: NP_005760.1, NP_001159867.1
Others
UniRef100: UniRef100_Q8NCG5
UniRef90: UniRef90_Q8NCG5
UniRef50: UniRef50_Q8NCG5
UniGene: Hs.251383
CCDS: CCDS10902.1

全选

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