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10163 WASF2

10163

WASF2

WASP family member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition WASP family member 2

研究结论

Date Results Publications
2021-03-20 13:27:00 MicroRNA-1253 Regulation of WASF2 (WAVE2) and its Relevance to Racial Health Disparities. 32443852
2019-11-09 11:42:00 High WAVE2 expression in pancreatic cancer tissues was correlated with overall survival. WAVE2 accumulated in the cell protrusions of pancreatic cancer cell lines through ACTN4 recruitment to filamentous actin in the protrusions and the activation of p27, resulting in an increase in motility and invasiveness of pancreatic ductal adenocarcinoma cells. 30353690
2018-11-03 10:03:00 Results show that in cisplatin-resistant cervical cancer tissues, Rac1, and Wave2 mRNA expression was significantly up-regulated compared to that of the cisplatin-sensitive cervical cancer tissues. In HeLa and Caski cervical cancer cell lines, Rac1 activity and Wave2 protein expression was significantly promoted by SH3BP1 overexpression. 28786507
2018-09-08 10:30:00 Studied leucine rich repeat kinase 2 (LRRK2)-WAS protein family member 2 (WAVE2) pathway in modulation of phagocytosis in leukocytes, as well as its possible role for altered immune function in Parkinson's Disease. 29760073
2017-09-16 11:08:00 The level of WASF2 in gastric cancer tissues was negatively correlated with miR-146a expression and had inverse clinicopathologic features. The newly identified miR-146a/WASF2 axis may provide a novel therapeutic target for gastric cancer. 28387985

名称对应

Type IDs
Synonymous IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2
Gene
UniProtKB-ID: WASF2_HUMAN
UniprotKB: Q9Y6W5
UniParc: UPI00017A848E, UPI0000000D74
EMBL: BC040943, AK303011, AL663122, AL096774, BX293535, AB026542
Ensembl: ENSG00000158195
KO: hsa:10163
Nucleutide sequences
EMBL-CDS: BAG64142.1, BAA81795.1, CAC18518.1, AAH40943.1
Ensembl_TRS: ENST00000618852, ENST00000536657
Protein sequencees
Ensembl_PRO: ENSP00000483313, ENSP00000439883
RefSeq: NP_008921.1, NP_001188333.1
Others
UniRef100: UniRef100_Q9Y6W5
UniRef90: UniRef90_Q9Y6W5
UniRef50: UniRef50_Q9Y6W5
UniGene: Hs.469244
CCDS: CCDS55582.1, CCDS304.1

全选

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