| Type | Description |
|---|---|
| Definition | lysophosphatidic acid receptor 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:18:00 | A distinctive protein signature induced by lysophosphatidic acid receptor 6 (LPAR6) expression in hepatocellular carcinoma cells. | 32321639 |
| 2020-10-24 14:03:00 | A potential target for liver cancer management, lysophosphatidic acid receptor 6 (LPAR6), is transcriptionally up-regulated by the NCOA3 coactivator. | 31914406 |
| 2019-12-14 12:01:00 | Study revealed a novel homozygous missense mutation c.47A>T (p.Lys16Met) in the LPAR6 gene in Pakistani family with autosomal recessive wooly hair/hypotrichosis. | 31077348 |
| 2019-06-22 12:31:00 | LPAR6 was downregulated in breast cancer(BC), and low LPAR6 expression was related to poor prognosis. The anti-tumor drug 5-Aza significantly upregulated LPAR6 expression in vitro, and LPAR6 might act as a tumor suppressor in BC. | 30694446 |
| 2019-03-30 13:11:00 | mRNA expression analyses revealed that ADSCs and MES largely expressed LPA receptor 1 (LPAR1) while epithelial cells mainly expressed LPAR6. LPA 18:1 activated all the cell populations and cell lines by rise in cytosolic free calcium concentrations. MES and ADSCs expressed ATX whereas epithelial cells did not. | 30567518 |
| Type | IDs |
|---|---|
| Synonymous | ARWH1, HYPT8, LAH3, P2RY5, P2Y5 |
| Gene |
UniProtKB-ID:
LPAR6_HUMAN,
B3KVQ5_HUMAN,
A0A024RDT2_HUMAN
UniprotKB:
P43657,
B3KVQ5,
A0A024RDT2
UniParc:
UPI00005A7B3B,
UPI0000001083
EMBL:
AL392048,
CH471075,
BX537392,
AF000546,
JF810890,
L78805,
BC040850,
AK123059,
HQ995530,
AK223389,
BX537438,
BX537445,
AF551763,
BC106756,
L11910,
BC070295,
AK122856,
BC045651
Ensembl:
ENSG00000139679
KO:
hsa:10161
|
| Nucleutide sequences |
EMBL-CDS:
CAD97687.1,
AAI06757.1,
EAX08796.1,
AAN64134.1,
BAD97109.1,
AAH70295.1,
AAH45651.1,
CAD97680.1,
AAL40065.1,
AEP43757.1,
BAG53764.1,
AAB62190.1,
ADZ31975.1,
CAD97634.1,
AAH40850.1,
BAG53867.1,
EAX08797.1
Gene_ORFName:
hCG_30749
Ensembl_TRS:
ENST00000620633,
ENST00000378434,
ENST00000345941
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482660,
ENSP00000367691,
ENSP00000344353
RefSeq:
NP_001364246.1,
XP_024305070.1,
NP_001155969.1,
NP_005758.2,
XP_024305071.1,
XP_024305072.1,
NP_001364245.1,
NP_001155970.1
|
| Others |
UniRef100:
UniRef100_P43657,
UniRef100_B3KVQ5
UniRef90:
UniRef90_P43657
UniRef50:
UniRef50_P43657
UniGene:
Hs.123464
CCDS:
CCDS9410.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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