| Type | Description |
|---|---|
| Definition | PDZK1 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 12:48:00 | Combined expression of fascin-1 and MAP17 in breast cancer cells is associated with a significantly worse 5-year PFS, therefore recognizing a group of patients with high risk for early disease recurrence. | 31273628 |
| 2019-10-19 11:15:00 | These findings indicate that PDZK1IP1 interacts with Smad4 and thereby suppresses the TGF-beta signaling pathway. | 30718277 |
| 2019-08-03 10:08:00 | MAP17 is overexpressed in most carcinomas and in many tumors of mesenchymal origin, and correlates with higher grade and poorly differentiated tumors. This overexpression drives deep changes in cell homeostasis including increased oxidative stress, deregulation of signaling pathways and increased growth rates. Importantly, MAP17 is associated not only in cancer but in various inflammatory diseases. [review] | 29650022 |
| 2019-06-29 11:11:00 | Membrane-associated protein 17 (MAP17) is shown to colocalize and coimmunoprecipitate with sodium/glucose cotransporter 2 (SGLT2). | 30156268 |
| 2018-10-20 11:17:00 | Our results indicate a potential prognostic role for MAP17 in lung tumours, with particular relevance in lung adenocarcinomas, and highlight the predictive pot0065ntial of this membrane-associated protein for platinum-based therapy and EGFR inhibitor efficacy. Furthermore, we propose bortezomib treatment as a novel and efficacious therapy for lung adenocarcinomas exhibiting high MAP17 expression. | 30119639 |
| Type | IDs |
|---|---|
| Synonymous | DD96, MAP17, SPAP |
| Gene |
UniProtKB-ID:
PDZ1I_HUMAN
UniprotKB:
Q13113
UniParc:
UPI000004EC8A
EMBL:
BC012303,
CH471059,
U21049,
AL135960,
CR450304
Ensembl:
ENSG00000162366
KO:
hsa:10158
|
| Nucleutide sequences |
EMBL-CDS:
CAB72104.1,
AAH12303.1,
AAA92690.1,
CAG29300.1,
EAX06878.1
Ensembl_TRS:
ENST00000294338,
ENST00000371885
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360952,
ENSP00000294338
RefSeq:
NP_005755.1
|
| Others |
UniRef100:
UniRef100_Q13113
UniRef90:
UniRef90_Q13113
UniRef50:
UniRef50_Q13113
UniGene:
Hs.431099
CCDS:
CCDS546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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