| Type | Description |
|---|---|
| Definition | plexin C1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 10:23:00 | Results indicated that PLXNC1 was a direct target of miR-4500. Its knockdown inhibits proliferation and invasion of papillary thyroid cancer (PTC) cells. On the contrary, its overexpression of impairs miR-4500-induced inhibition of PTC malignancy. | 31317324 |
| 2018-10-06 10:19:00 | Results indicate that long non-coding RNA (lncRNA) CASC2 can promote PLXNC1 expression by sponging miR-181a, thereby inhibiting the proliferation and invasion of melanoma cells. | 29514220 |
| 2017-09-23 13:24:00 | Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis | 27609773 |
| 2013-12-07 12:09:00 | loss of Plexin C1 in melanoma may promote early steps in melanoma progression through suppression of migration and proliferation | 23160370 |
| 2010-09-27 12:28:00 | Study reports the structures of Sema7A and A39R complexed with the Semaphorin-binding module of PlexinC1; both structures show two PlexinC1 molecules symmetrically bridged by Semaphorin dimers. | 20727575 |
| Type | IDs |
|---|---|
| Synonymous | CD232, PLXN-C1, VESPR |
| Gene |
UniProtKB-ID:
PLXC1_HUMAN
UniprotKB:
O60486
UniParc:
UPI0000038AF4
EMBL:
AB208934,
AF030339
Ensembl:
ENSG00000136040
KO:
hsa:10154
|
| Nucleutide sequences |
EMBL-CDS:
AAC18823.1,
BAD92171.1
Ensembl_TRS:
ENST00000258526
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258526
RefSeq:
XP_011536032.1,
XP_016874161.1,
XP_011536033.1,
XP_016874160.1,
XP_006719249.1,
NP_005752.1
|
| Others |
UniRef100:
UniRef100_O60486
UniRef90:
UniRef90_O60486
UniRef50:
UniRef50_O60486
UniGene:
Hs.584845
CCDS:
CCDS9049.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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