| Type | Description |
|---|---|
| Definition | RIC8 guanine nucleotide exchange factor A |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 11:23:00 | In conditional Ric8a knockout mice the absence of RIC8A severely affected the attachment and positioning of radial glial processes, Cajal-Retzius' cells, and the arachnoid trabeculae, and these mice displayed additional defects in the lens, skeletal muscles, and heart development. All the discovered defects might be linked to aberrancies in cell adhesion and migration. | 29380551 |
| 2017-10-14 10:56:00 | found that RIC8A plays an important role in the organisation and remodelling of actin cytoskeleton and cell-extracellular matrix association | 28526238 |
| 2016-05-21 11:58:00 | Results suggest that RIC8A has an essential role in the development of mammalian nervous system by maintaining the integrity of pial basement membrane and modulating cell division | 25641781 |
| 2016-04-23 11:37:00 | Data show that the localization of maternally expressed RIC8 protein is highly dynamic and is dependent on the stage of folliculogenesis, oogenesis and cleavage, and imply that it may have a regulatory function in mammalian gametogenesis. | 26062014 |
| 2015-12-19 11:54:00 | Data show that disrupting resistance to inhibitors of cholinesterase 8A (Ric-8A) expression in hematopoietic cells results in a loss of GTP-binding protein alpha subunits Galphai2, Galphai3, and Galphaq. | 26232433 |
| Type | IDs |
|---|---|
| Synonymous | AI114950, RIC-8, Ric8 |
| Gene |
UniProtKB-ID:
RIC8A_MOUSE
UniprotKB:
Q3TIR3
UniParc:
UPI0000022638
EMBL:
AF288813,
AK167746,
AK031466,
AK080192,
BC022917,
AK155282,
AK169367
Ensembl:
ENSMUSG00000025485
KO:
mmu:101489
|
| Nucleutide sequences |
EMBL-CDS:
BAE41115.1,
BAE33163.1,
AAG10200.1,
BAC27418.1,
BAC37844.1,
BAE39783.1,
AAH22917.1
Ensembl_TRS:
ENSMUST00000026558
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026558
RefSeq:
NP_444424.1
|
| Others |
UniRef100:
UniRef100_Q3TIR3
UniRef90:
UniRef90_Q3TIR3
UniRef50:
UniRef50_Q9NPQ8-3
UniGene:
Mm.281916
CCDS:
CCDS21988.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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