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10143 CLEC3A

10143

CLEC3A

C-type lectin domain family 3 member A

protein-coding

Homo sapiens

基因描述

Type Description
Definition C-type lectin domain family 3 member A

研究结论

Date Results Publications
2021-02-06 13:58:00 Suppression of CLEC3A inhibits osteosarcoma cell proliferation and promotes their chemosensitivity through the AKT1/mTOR/HIF1alpha signaling pathway. 32319617
2020-08-12 15:16:00 we demonstrated that the recurrence potential in PNETs is characterized by the upregulation of genes related to ECM organization and cell adhesion. This study identified three genes-CLEC3, MMP7, and LCN2-that contribute to the prediction of postoperative recurrence of PNETs in clinical practice. 31129920
2010-01-21 00:00:00 CLEC3A binds to heparan sulfate proteoglycans on cell surface, leading to the enhancement of cell adhesion to integrin ligands on ECM; cleavage of CLEC3A by MMP-7 weakens the stable adhesion of tumor cells to the matrix 19173304
2009-12-02 21:41:00 Observational study of gene-disease association. (HuGE Navigator) 19844255

名称对应

Type IDs
Synonymous CLECSF1
Gene
UniProtKB-ID: CLC3A_HUMAN, J3KNC9_HUMAN
UniprotKB: O75596, J3KNC9
UniParc: UPI000004A9A6, UPI00001FFC6A
EMBL: AY358376, AC079414, AF077345, CH471114, AK313316, BC104415, AF077344
Ensembl: ENSG00000166509
KO: hsa:10143
Nucleutide sequences
EMBL-CDS: AAQ88742.1, AAI04416.1, AAD12542.1, BAG36121.1, EAW95593.1
Gene_ORFName: UNQ700/PRO1345, hCG_1645201
Ensembl_TRS: ENST00000299642, ENST00000651443
Protein sequencees
Ensembl_PRO: ENSP00000299642, ENSP00000499168
RefSeq: NP_005743.5
Others
UniRef100: UniRef100_O75596
UniRef90: UniRef90_O75596
UniRef50: UniRef50_O75596
UniGene: Hs.177936
CCDS: CCDS10927.2

全选

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研究热度

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